{"product_id":"aldoc-monoclonal-antibody-mb66856","title":"ALDOC Monoclonal Antibody-MB66856","description":"\u003cp\u003eALDOC Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: MB66856-50, MB66856-100\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eProduct: Mouse IgG3. Liquid in PBS, pH 7.3, 30% glycerol, and 0.01% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: P09972\u003c\/p\u003e\n\n\u003cp\u003eHost: Mouse\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB\u003c\/p\u003e\n\n\u003cp\u003eAll Applications: WB (1\/500 - 1\/1000), FC (1\/10 - 1\/50)\u003c\/p\u003e\n\n\u003cp\u003eBackground: Aldolase (fructose bisphosphate aldolase), a glycolytic enzyme, catalyzes the conversion of fructose 1, 6-bisphosphate to 3-phosphoglyceraldehyde. This ubiquitous enzyme is present as three different isozymes: aldolase A, aldolase B, and aldolase C. Research studies suggest that aldolase A expression potentially differentiates between nonneoplastic liver diseases and hepatocarcinoma . Furthermore, investigators have shown that changes in aldolase B gene expression levels have been observed in certain patients with this primary tumor .Aldolase C is primarily expressed in the central nervous system . Studies have shown increased detection of serum aldolase C following traumatic brain injury (TBI) and mild TBI, showing potential for aldolase C as a biomarker for TBI.\u003c\/p\u003e \n\n\u003cp\u003ePurification and Purity: This antibody is purified through a protein G column.\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: Recognizes endogenous levels of ALDOC protein.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Western blot analysis of ALDOC expression in HL60 (A), 293T (B), mouse brain (C), rat brain (D), mouse spleen (E) whole cell lysates.\u003c\/p\u003e\n\n\u003cp\u003eBioworld Molecular Weight: ~ 41 kDa\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: ALDC; Fructose-bisphosphate aldolase C; Brain-type aldolase\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant fusion protein of human ALDOC. The exact sequence is proprietary.\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42906389348531,"sku":"MB66856-50","price":260.23,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42906389381299,"sku":"MB66856-100","price":452.94,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_c61dca61-ca88-450c-8a92-75cc319d5021.jpg?v=1702918954","url":"https:\/\/afsbio.com\/products\/aldoc-monoclonal-antibody-mb66856","provider":"AFSBio Inc.","version":"1.0","type":"link"}