{"product_id":"aldolase-a-polyclonal-antibody-bt-ap00364","title":"Aldolase A Polyclonal Antibody - BT-AP00364","description":"\u003cp\u003eAldolase A Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP00364-20, BT-AP00364-50, BT-AP00364-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: The protein encoded by ALDOA, Aldolase A (fructose-bisphosphate aldolase), is a glycolytic enzyme that catalyzes the reversible conversion of fructose-1,6-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. Three aldolase isozymes (A, B, and C), encoded by three different genes, are differentially expressed during development. Aldolase A is found in the developing embryo and is produced in even greater amounts in adult muscle. Aldolase A expression is repressed in adult liver, kidney and intestine and similar to aldolase C levels in brain and other nervous tissue. Aldolase A deficiency has been associated with myopathy and hemolytic anemia. Alternative splicing and alternative promoter usage results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 3 and 10.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Signal Transduction; Metabolism\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: ALDOA\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IF, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Aldolase A Antibody\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 39420\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: P04075; Mouse: P05064; Rat: P05065\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: ALDOA; ALDA; Fructose-bisphosphate aldolase A; Lung cancer antigen NY-LU-1; Muscle-type aldolase\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 226; Mouse: 11674; Rat: 24189\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45240104026291,"sku":"BT-AP00364-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45240104059059,"sku":"BT-AP00364-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45240104091827,"sku":"BT-AP00364-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_6413469f-e3d3-4f80-bfcc-0d40cba36844.png?v=1769403454","url":"https:\/\/afsbio.com\/products\/aldolase-a-polyclonal-antibody-bt-ap00364","provider":"AFSBio Inc.","version":"1.0","type":"link"}