{"product_id":"aldose-reductase-polyclonal-antibody-bt-ap00368","title":"Aldose Reductase Polyclonal Antibody - BT-AP00368","description":"\u003cp\u003eAldose Reductase Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP00368-20, BT-AP00368-50, BT-AP00368-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: AKR1B1 encodes a member of the aldo\/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. This member (aldo-keto reductase family 1 member B) catalyzes the reduction of a number of aldehydes, including the aldehyde form of glucose, and is thereby implicated in the development of diabetic complications by catalyzing the reduction of glucose to sorbitol. Multiple pseudogenes have been identified for this gene. The nomenclature system used by the HUGO Gene Nomenclature Committee to define human aldo-keto reductase family members is known to differ from that used by the Mouse Genome Informatics database.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Signal Transduction; Metabolism\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: AKR1B1\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC-p, IF, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Rat\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Aldose Reductase Antibody\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 35853\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: P15121; Mouse: P45376; Rat: P07943\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: AKR1B1; ALDR1; Aldose reductase; AR; Aldehyde reductase; Aldo-keto reductase family 1 member B1\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 231; Rat: 24192\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45240104419507,"sku":"BT-AP00368-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45240104452275,"sku":"BT-AP00368-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45240104485043,"sku":"BT-AP00368-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_1d7a000f-d6f2-45bf-a6af-71e2c19d2d79.png?v=1769403460","url":"https:\/\/afsbio.com\/products\/aldose-reductase-polyclonal-antibody-bt-ap00368","provider":"AFSBio Inc.","version":"1.0","type":"link"}