{"product_id":"alk-1-polyclonal-antibody-bt-ap00374","title":"ALK-1 Polyclonal Antibody - BT-AP00374","description":"\u003cp\u003eALK-1 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP00374-20, BT-AP00374-50, BT-AP00374-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: ACVRL1 encodes a type I cell-surface receptor for the TGF-beta superfamily of ligands. It shares with other type I receptors a high degree of similarity in serine-threonine kinase subdomains, a glycine- and serine-rich region (called the GS domain) preceding the kinase domain, and a short C-terminal tail. The encoded protein, sometimes termed ALK1, shares similar domain structures with other closely related ALK or activin receptor-like kinase proteins that form a subfamily of receptor serine\/threonine kinases. Mutations in this gene are associated with hemorrhagic telangiectasia type 2, also known as Rendu-Osler-Weber syndrome 2.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cardiovascular; Signal Transduction\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: ACVRL1\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC-p, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: ALK-1 Antibody\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 56124\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: P37023; Mouse: Q61288; Rat: P80203\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: ACVRL1; ACVRLK1; ALK1; Serine\/threonine-protein kinase receptor R3; SKR3; Activin receptor-like kinase 1; ALK-1; TGF-B superfamily receptor type I; TSR-I\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 94; Mouse: 11482; Rat: 25237\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45240105009331,"sku":"BT-AP00374-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45240105042099,"sku":"BT-AP00374-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45240105074867,"sku":"BT-AP00374-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_6ab8aed7-3a9c-4fe7-aea3-977e106489e9.png?v=1769403469","url":"https:\/\/afsbio.com\/products\/alk-1-polyclonal-antibody-bt-ap00374","provider":"AFSBio Inc.","version":"1.0","type":"link"}