{"product_id":"alkb3-polyclonal-antibody-bt-ap14185","title":"ALKB3 Polyclonal Antibody - BT-AP14185","description":"\u003cp\u003eALKB3 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP14185-20, BT-AP14185-50, BT-AP14185-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: The Escherichia coli AlkB protein protects against the cytotoxicity of methylating agents by repair of the specific DNA lesions generated in single-stranded DNA. ALKBH2 (MIM 610602) and ALKBH3 are E. coli AlkB homologs that catalyze the removal of 1-methyladenine and 3-methylcytosine (Duncan et al., 2002\u003c\/p\u003e \n\n\u003cp\u003eResearch Areas: Epigenetics and nuclear signaling\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: ALKBH3\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Rat, Mouse\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Alpha-ketoglutarate-dependent dioxygenase alkB homolog 3\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: Q96Q83; Mouse: Q8K1E6; Rat: Q5XIC8\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: Alpha-ketoglutarate-dependent dioxygenase alkB homolog 3;EC 1.14.11.-;Alkylated DNA repair protein alkB homolog 3;DEPC-1;Prostate cancer antigen 1\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 221120\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239048503475,"sku":"BT-AP14185-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239048536243,"sku":"BT-AP14185-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239048569011,"sku":"BT-AP14185-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_bc414b5e-63fb-41fe-88ca-bffee655e693.png?v=1769388390","url":"https:\/\/afsbio.com\/products\/alkb3-polyclonal-antibody-bt-ap14185","provider":"AFSBio Inc.","version":"1.0","type":"link"}