{"product_id":"alr-rabbit-polyclonal-antibody-es4259","title":"ALR Rabbit Polyclonal Antibody - ES4259","description":"\u003cp\u003eALR Rabbit Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: ES4259-50, ES4259-100\u003c\/p\u003e\n\n\u003cp\u003eLead times: 1-2 weeks, if manufacturer has product in stock\u003c\/p\u003e\n\n\u003cp\u003eManufacturer\/Ship Location: China\u003c\/p\u003e\n\n\u003cp\u003eBackground: The hepatotrophic factor designated augmenter of liver regeneration (ALR) is thought to be one of the factors responsible for the extraordinary regenerative capacity of mammalian liver. It has also been called hepatic regenerative stimulation substance (HSS). The gene resides on chromosome 16 in the interval containing the locus for polycystic kidney disease (PKD1). The putative gene product is 42% similar to the scERV1 protein of yeast. The yeast scERV1 gene had been found to be essential for oxidative phosphorylation, the maintenance of mitochondrial genomes, and the cell division cycle. The human gene is both the structural and functional homolog of the yeast scERV1 gene. [provided by RefSeq, Jul 2008],\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC, IF, ELISA\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: GFER, ALR, HERV1, HPO, FAD-linked sulfhydryl oxidase ALR, Augmenter of liver regeneration, hERV1, Hepatopoietin\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from the Internal region of human GFER. AA range:51-100\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eTarget: ALR\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: ALR Polyclonal Antibody detects endogenous levels of ALR protein.\u003c\/p\u003e\n\n\u003cp\u003eDilution: Western Blot: 1\/500 - 1\/2000. IHC-p: 1:100-1:300. ELISA: 1\/20000. Not yet tested in other applications.\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml,\u003c\/p\u003e\n\n\u003cp\u003eFormlation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eExpression: Ubiquitously expressed, Highest expression in the testis and liver and low expression in the muscle,\u003c\/p\u003e\n\n\u003cp\u003eObserved Band (KD): 24kD\u003c\/p\u003e\n\n\u003cp\u003eFunction: Catalytic Activity: 4 R'C(R)SH + O(2) = 2 R'C(R)S-S(R)CR' + 2 H(2)O\u003cbr\u003e\nCofactor: FAD\u003cbr\u003e\nFunction: FAD-dependent sulfhydryl oxidase that catalyzes disulfide bond formation\u003cbr\u003e\nSimilarity: Contains 1 ERV\/ALR sulfhydryl oxidase domain\u003cbr\u003e\nSubunit: Homodimer\u003c\/p\u003e\n\n\n\u003cp\u003eSubcellular Location: [Isoform 1]: Mitochondrion intermembrane space Mitochondrion, [Isoform 2]: Cytoplasm Secreted\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eGene Name: GFER\u003c\/p\u003e\n\n\u003cp\u003eProtein Name: FAD-linked sulfhydryl oxidase ALR\u003c\/p\u003e\n\n\u003cp\u003eMouse Gene ID: 11692\u003c\/p\u003e\n\n\u003cp\u003eMouse SwissProt Number: P56213\u003c\/p\u003e\n\n\u003cp\u003eRat Gene ID: 27100\u003c\/p\u003e\n\n\u003cp\u003eRat SwissProt Number: Q63042\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ELK Biotechnology","offers":[{"title":"50μL","offer_id":46316569919667,"sku":"ES4259-50","price":186.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":46316569952435,"sku":"ES4259-100","price":372.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/elk_antibodies_d75295e2-ffc1-4e0f-a3e7-87715c8983a9.jpg?v=1793190507","url":"https:\/\/afsbio.com\/products\/alr-rabbit-polyclonal-antibody-es4259","provider":"AFSBio Inc.","version":"1.0","type":"link"}