{"product_id":"amacr-monoclonal-antibody-4a12-ra10755","title":"AMACR Monoclonal Antibody (4A12) - RA10755","description":"\u003cp\u003eAMACR Monoclonal Antibody (4A12)\u003c\/p\u003e \n\n\u003cp\u003eSize: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: RA10755-50, RA10755-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: alpha-methylacyl-CoA racemase (AMACR) Homo sapiens This gene encodes a racemase. The encoded enzyme interconverts pristanoyl-CoA and C27-bile acylCoAs between their (R) - and (S) -stereoisomers. The conversion to the (S) -stereoisomers is necessary for degradation of these substrates by peroxisomal beta-oxidation. Encoded proteins from this locus localize to both mitochondria and peroxisomes. Mutations in this gene may be associated with adult-onset sensorimotor neuropathy, pigmentary retinopathy, and adrenomyeloneuropathy due to defects in bile acid synthesis. Alternatively spliced transcript variants have been described. Read-through transcription also exists between this gene and the upstream neighboring C1QTNF3 (C1q and tumor necrosis factor related protein 3) gene. [provided by RefSeq, Mar 2011],\u003c\/p\u003e\n\n\u003cp\u003eCondition: PBS, pH 7.4, containing 0.5% BSA, 0.02% sodium azide as Preservative and 50% Glycerol.\u003c\/p\u003e\n\n\u003cp\u003eStorage Instructions: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB; IF\/ICC; IHC-p\u003c\/p\u003e\n\n\u003cp\u003eSpecies Cross-Reactivity: Human; Mouse; Rat\u003c\/p\u003e\n\n\u003cp\u003eGeneID (Human): 23600\u003c\/p\u003e\n\n\u003cp\u003eProtein MW (KDa): 42\u003c\/p\u003e\n\n\u003cp\u003eSWISS: Q9UHK6\u003c\/p\u003e\n\n\u003cp\u003eSource: Mouse\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Reed Bio","offers":[{"title":"50μL","offer_id":45119020990643,"sku":"RA10755-50","price":336.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45119021023411,"sku":"RA10755-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_8f8016d5-4fc5-4fcb-8020-51266180d000.png?v=1773344348","url":"https:\/\/afsbio.com\/products\/amacr-monoclonal-antibody-4a12-ra10755","provider":"AFSBio Inc.","version":"1.0","type":"link"}