{"product_id":"amacr-polyclonal-antibody-e-ab-60199","title":"AMACR Polyclonal Antibody - E-AB-60199","description":"\u003cp\u003eAMACR Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-60199-60, E-AB-60199-120, E-AB-60199-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: AMACR\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: AMACR; AMACRD; CBAS4; P504S; RACE; RM\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cell Biology, Metabolism, Signal Transduction\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplication: WB\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n \n\n\u003cp\u003eUNIProt ID: Q9UHK6\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a racemase. The encoded enzyme interconverts pristanoyl-CoA and C27-bile acylCoAs between their (R)- and (S)-stereoisomers. The conversion to the (S)-stereoisomers is necessary for degradation of these substrates by peroxisomal beta-oxidation. Encoded proteins from this locus localize to both mitochondria and peroxisomes. Mutations in this gene may be associated with adult-onset sensorimotor neuropathy, pigmentary retinopathy, and adrenomyeloneuropathy due to defects in bile acid synthesis. Alternatively spliced transcript variants have been described. Read-through transcription also exists between this gene and the upstream neighboring C1QTNF3 (C1q and tumor necrosis factor related protein 3) gene.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant fusion protein of human AMACR (NP_976316.1).\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB \t1:500-1:2000\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 22kDa\/25kDa\/42kDa\/43kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 43kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"60μL","offer_id":43146043523251,"sku":"E-AB-60199-60","price":280.0,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43146043556019,"sku":"E-AB-60199-120","price":448.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43146043588787,"sku":"E-AB-60199-200","price":742.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_dd3ddebd-2bb9-4e07-bad9-531e4fef9f3f.png?v=1710290475","url":"https:\/\/afsbio.com\/products\/amacr-polyclonal-antibody-e-ab-60199","provider":"AFSBio Inc.","version":"1.0","type":"link"}