{"product_id":"amigo2-polyclonal-antibody-e-ab-10790","title":"AMIGO2 Polyclonal Antibody - E-AB-10790","description":"\u003cp\u003eAMIGO2 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-10790-60, E-AB-10790-120, E-AB-10790-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: AMIGO2\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: Adhesion molecule with Ig like domain 2; ALI 1; ALI1; Alivin 1; Alivin-1; Alivin1; AMGO2; AMIGO 2; AMIGO-2; Amigo2; Amphoterin induced gene 2; Amphoterin induced protein 2; Amphoterin-induced gene and open reading frame 2; Amphoterin-induced protein 2; DEGA; Differentially expressed in gastric adenocarcinoma; Differentially expressed in gastric adenocarcinomas; Transmembrane protein AMIGO 2; Transmembrane protein AMIGO2\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Neuroscience\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplication: WB, IHC, ELISA\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n \n\n\u003cp\u003eUNIProt ID: Q86SJ2\u003c\/p\u003e\n\n\u003cp\u003eBackground: The amphoterin-induced gene and ORF (AMIGO) family of proteins consists of AMIGO-1, AMIGO-2 and AMIGO-3. All three members are single pass type I membrane proteins that contain several leucine-rich repeats, one IgG domain, and a transmembrane domain. The AMIGO proteins are specifically expressed on fiber tracts of neuronal tissues and participate in their formation. The AMIGO proteins can form complexes with each other, but can also bind itself. AMIGO-1, also designated Alivin-2, promotes growth and fasciculation of neurites and plays a role in myelination and fasciculation of developing neural axons. In cerebellar neurons, AMIGO-2 (Alivin-1) is crucial for depolarization-dependent survival. Similar to AMIGO-1 and AMIGO-2, AMIGO-3 (Alivin-3) plays a role in homophilic and\/or heterophilic cell-cell interaction and signal transduction\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 0.5 mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant protein of human AMIGO2\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1:500-1:2000, IHC 1:50-1:200\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 58kDa\u003c\/p\u003e\n\n \n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"60μL","offer_id":43136083394739,"sku":"E-AB-10790-60","price":200.2,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43136083427507,"sku":"E-AB-10790-120","price":336.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43136083460275,"sku":"E-AB-10790-200","price":558.6,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_7beed239-a2f9-4d70-bdcb-ad2445ecedac.png?v=1709987699","url":"https:\/\/afsbio.com\/products\/amigo2-polyclonal-antibody-e-ab-10790","provider":"AFSBio Inc.","version":"1.0","type":"link"}