{"product_id":"amphiregulin-rabbit-pab-es4371","title":"Amphiregulin rabbit pAb - ES4371","description":"\u003cp\u003eAmphiregulin rabbit pAb\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: ES4371-50, ES4371-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: The protein encoded by this gene is a member of the epidermal growth factor family. It is an autocrine growth factor as well as a mitogen for astrocytes, Schwann cells and fibroblasts. It is related to epidermal growth factor (EGF) and transforming growth factor alpha (TGF-alpha). The protein interacts with the EGF\/TGF-alpha receptor to promote the growth of normal epithelial cells, and it inhibits the growth of certain aggressive carcinoma cell lines. It also functions in mammary gland, oocyte and bone tissue development. This gene is associated with a psoriasis-like skin phenotype, and is also associated with other pathological disorders, including various types of cancers and inflammatory conditions. [provided by RefSeq, Apr 2014],\u003c\/p\u003e \n\n\u003cp\u003eAlternate Name: AREG; SDGF; AREGB; Amphiregulin; AR; Colorectum cell-derived growth factor; CRDGF\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB; ELISA\u003c\/p\u003e\n\n\u003cp\u003eDilution: Western Blot: 1\/500 - 1\/2000. ELISA: 1\/10000. Not yet tested in other applications.\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human; Rat; Mouse;\u003c\/p\u003e \n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from the Internal region of human AREG\/AREGB. AA range:91-140\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eObserved Band (KD): 17kD\u003c\/p\u003e\n\n\u003cp\u003eHuman Gene ID: 374\/727738\u003c\/p\u003e\n\n\u003cp\u003eHuman SWISS Prot NO: P15514\u003c\/p\u003e\n\n\u003cp\u003eSubcellular Location: Membrane; Single-pass membrane protein.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ELK Bio","offers":[{"title":"50μL","offer_id":45202193449139,"sku":"ES4371-50","price":207.2,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45202193481907,"sku":"ES4371-100","price":347.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_360x_eda9bcfa-ba25-4edd-a8db-b702aa1d5bca.png?v=1767123947","url":"https:\/\/afsbio.com\/products\/amphiregulin-rabbit-pab-es4371","provider":"AFSBio Inc.","version":"1.0","type":"link"}