{"product_id":"ampkα1-2-phospho-thr183-172-polyclonal-antibody-ra20489","title":"AMPKα1\/2 (phospho Thr183\/172) Polyclonal Antibody - RA20489","description":"AMPKα1\/2 (phospho Thr183\/172) Polyclonal Antibody\n\nSizes: 50μL, 100μL\n\nCatalogue Numbers: RA20489-50, RA20489-100\n\nCitations, Manuals and MSDS Available upon request.\n\nBackground: protein kinase AMP-activated catalytic subunit alpha 1 (PRKAA1) Homo sapiens The protein encoded by this gene belongs to the ser\/thr protein kinase family. It is the catalytic subunit of the 5'-prime-AMP-activated protein kinase (AMPK) . AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP\/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008],\n\nCondition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\n\nStorage Instructions: -20°C\/1 year\n\nRecommended dilutions: IF: 1:50-200 Western Blot: 1\/500 - 1\/2000. Immunohistochemistry: 1\/100 - 1\/300. ELISA: 1\/40000. Not yet tested in other applications.\n\nAlternative Names: PRKAA1; AMPK1; 5'-AMP-activated protein kinase catalytic subunit alpha-1; AMPK subunit alpha-1; Acetyl-CoA carboxylase kinase; ACACA kinase; Hydroxymethylglutaryl-CoA reductase kinase; HMGCR kinase; Tau-protein kinase PRKAA1; PRKAA2; AMPK;\n\nApplications: IF\/ICC; WB; IHC-p; ELISA\n\nSpecies Cross-Reactivity: Human; Mouse; Rat; Monkey; Pig\n\nGeneID (Human): 5562\/5563\n\nProtein MW (KDa): 63\n\nSWISS: Q13131\/P54646\n\nSource: Rabbit\n\nResearch Use Only","brand":"Reed Bio","offers":[{"title":"50μL","offer_id":45120671187123,"sku":"RA20489-50","price":336.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45120671219891,"sku":"RA20489-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_77605132-d639-4ef8-a76f-176b31dab582.png?v=1773369250","url":"https:\/\/afsbio.com\/products\/ampk%ce%b11-2-phospho-thr183-172-polyclonal-antibody-ra20489","provider":"AFSBio Inc.","version":"1.0","type":"link"}