{"product_id":"ampkα1-polyclonal-antibody-e-ab-66996","title":"AMPKα1 Polyclonal Antibody - E-AB-66996","description":"AMPKα1 Polyclonal Antibody\n\nSizes: 60μL, 120μL, 200μL\n\nCatalogue Numbers: E-AB-66996-60, E-AB-66996-120, E-AB-66996-200\n\nCitations, Manuals and MSDS Available upon request.\n\nAbbreviation: AMPKα1\n\nTarget Synonym: PRKAA1; AMPK; AMPKa1\n\nResearch Areas: Cancer, Cardiovascular, Metabolism, Neuroscience, Signal Transduction\n\nConjugation: Unconjugated\n\nHost: Rabbit\n\nSpecies Reactivity: Human, Mouse, Rat\n\nApplication: IHC\n\nIsotype: IgG\n\nClonality: Polyclonal\n\n \n\nUNIProt ID: Q13131\n\nBackground: The protein encoded by this gene belongs to the ser\/thr protein kinase family. It is the catalytic subunit of the 5'-prime-AMP-activated protein kinase (AMPK). AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP\/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. Alternatively spliced transcript variants encoding distinct isoforms have been observed.\n\nConcentration: 1mg\/mL\n\nImmunogen: A synthetic peptide of human AMPKα1 alpha 1\n\nBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.\n\nPurification Method: Affinity purification\n\nDilution: IHC 1:50-1:200\n\n \n\n \n\nStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\n\nShipping: Ice bag\n\nResearch Use Only","brand":"Elabscience","offers":[{"title":"60μL","offer_id":43135884132531,"sku":"E-AB-66996-60","price":280.0,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43135884165299,"sku":"E-AB-66996-120","price":448.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43135884198067,"sku":"E-AB-66996-200","price":742.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_2cbfe4b6-da1d-421b-82d0-3e0a5b17aeaf.png?v=1709985875","url":"https:\/\/afsbio.com\/products\/ampk%ce%b11-polyclonal-antibody-e-ab-66996","provider":"AFSBio Inc.","version":"1.0","type":"link"}