{"product_id":"ampkalpha-1-2-polyclonal-antibody-bt-ap00084","title":"AMPKAlpha 1\/2 Polyclonal Antibody - BT-AP00084","description":"\u003cp\u003eAMPKAlpha 1\/2 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP00084-20, BT-AP00084-50, BT-AP00084-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: The protein encoded by this gene belongs to the ser\/thr protein kinase family. It is the catalytic subunit of the 5'-prime-AMP-activated protein kinase (AMPK). AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP\/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. Alternatively spliced transcript variants encoding distinct isoforms have been observed.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Metabolism\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: AAPK1\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC-p, IF, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat, Monkey\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: PRKAA1\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 62808;62320\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: Q13131\/P54646; Rat: P54645\/Q09137\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: PRKAA1; PRKAA1; AMPK1; 5'-AMP-activated protein kinase catalytic subunit alpha-1; AMPK subunit alpha-1; Acetyl-CoA carboxylase kinase; ACACA kinase; Hydroxymethylglutaryl-CoA reductase kinase; HMGCR kinase; Tau-protein kinase PRKAA1; PRKAA2; AMPK;\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 5562\/5563; Mouse: 105787\/108079; Rat: 65248\/78975\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45240024629427,"sku":"BT-AP00084-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45240024662195,"sku":"BT-AP00084-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45240024694963,"sku":"BT-AP00084-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_f8b3a413-f723-45b1-bf65-458e33b311a5.png?v=1769402302","url":"https:\/\/afsbio.com\/products\/ampkalpha-1-2-polyclonal-antibody-bt-ap00084","provider":"AFSBio Inc.","version":"1.0","type":"link"}