{"product_id":"ampkalpha-1-phospho-ser485-rabbit-polyclonal-antibody-bt-ap00381","title":"AMPKAlpha 1 (Phospho-Ser485) Rabbit Polyclonal Antibody - BT-AP00381","description":"\u003cp\u003eAMPKAlpha 1 (Phospho-Ser485) Rabbit Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP00381-20, BT-AP00381-50, BT-AP00381-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: The protein encoded by this gene belongs to the ser\/thr protein kinase family. It is the catalytic subunit of the 5andapos;-prime-AMP-activated protein kinase (AMPK). AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP\/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. Alternatively spliced transcript variants encoding distinct isoforms have been observed.\u003c\/p\u003e \n\n\u003cp\u003eResearch Areas: Cardiovascular; Signal transduction; Cancer; Metabolism; Neuroscience; Epigenetics and nuclear signaling\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: AMPK1\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: AMPKalpha 1\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: Q13131; Mouse: Q5EG47; Rat: P54645\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: AMPKα1 (Ser485); 5'-AMP-activated protein kinase catalytic subunit alpha-1; AMPK subunit alpha-1; EC 2.7.11.1; Acetyl-CoA carboxylase kinase; ACACA kinase; EC 2.7.11.27; Hydroxymethylglutaryl-CoA reductase kinase; HMGCR kinase; EC 2.7.11.31; Tau-protein kinase PRKAA1; EC 2.7.11.26)\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 5562; Mouse: 105787; Rat: 65248\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45238963699891,"sku":"BT-AP00381-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45238963732659,"sku":"BT-AP00381-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45238963765427,"sku":"BT-AP00381-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_08e759ea-39b1-4c95-98c6-4dee80a68224.png?v=1769387325","url":"https:\/\/afsbio.com\/products\/ampkalpha-1-phospho-ser485-rabbit-polyclonal-antibody-bt-ap00381","provider":"AFSBio Inc.","version":"1.0","type":"link"}