{"product_id":"anapc15-polyclonal-antibody-e-ab-19631","title":"ANAPC15 Polyclonal Antibody - E-AB-19631","description":"\u003cp\u003eANAPC15 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-19631-60, E-AB-19631-120, E-AB-19631-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: ANAPC15\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: ANAPC15; Anaphase-promoting complex subunit 15; C11orf51; CK051; HSPC020; Uncharacterized protein C11orf51\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cell Biology\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplication: IHC, ELISA\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n \n\n\u003cp\u003eUNIProt ID: P60006\u003c\/p\u003e\n\n\u003cp\u003eBackground: ANAPC15 is a component of the anaphase promoting complex\/cyclosome (APC\/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. In the complex, it plays a role in the release of the mitotic checkpoint complex (MCC) from the APC\/C: not required for APC\/C activity itself, but promotes the turnover of CDC20 and MCC on the APC\/C, thereby participating to the responsiveness of the spindle assembly checkpoint. It is also required for degradation of CDC20.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1.2 mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthetic peptide of human ANAPC15\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Antigen affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: IHC 1:40-1:200, ELISA 1:5000-1:10000\u003c\/p\u003e\n\n \n\n \n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"60μL","offer_id":43133411000499,"sku":"E-AB-19631-60","price":200.2,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43133411033267,"sku":"E-AB-19631-120","price":336.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43133411066035,"sku":"E-AB-19631-200","price":558.6,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_d81bf5d9-ff47-45ca-a674-d130e46172f2.png?v=1709898650","url":"https:\/\/afsbio.com\/products\/anapc15-polyclonal-antibody-e-ab-19631","provider":"AFSBio Inc.","version":"1.0","type":"link"}