{"product_id":"angpt1-polyclonal-antibody-e-ab-62625","title":"ANGPT1 Polyclonal Antibody - E-AB-62625","description":"\u003cp\u003eANGPT1 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-62625-60, E-AB-62625-120, E-AB-62625-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: ANGPT1\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: ANGPT1; AGP1; AGPT; ANG1\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cancer, Cardiovascular, Metabolism\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplication: WB, IHC\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n \n\n\u003cp\u003eUNIProt ID: Q15389\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a secreted glycoprotein that belongs to the angiopoietin family. Members of this family play important roles in vascular development and angiogenesis. All angiopoietins bind with similar affinity to an endothelial cell-specific tyrosine-protein kinase receptor. The protein encoded by this gene is a secreted glycoprotein that activates the receptor by inducing its tyrosine phosphorylation. It plays a critical role in mediating reciprocal interactions between the endothelium and surrounding matrix and mesenchyme and inhibits endothelial permeability. The protein also contributes to blood vessel maturation and stability, and may be involved in early development of the heart. Alternative splicing results in multiple transcript variants encoding distinct isoforms.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant fusion protein of human ANGPT1 (NP_001186788.1).\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB \t1:500-1:2000   IHC \t1:50-1:100\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 57kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 51kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"60μL","offer_id":43146251993267,"sku":"E-AB-62625-60","price":280.0,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43146252026035,"sku":"E-AB-62625-120","price":448.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43146252058803,"sku":"E-AB-62625-200","price":742.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_e491da33-8e11-4b6a-9189-e1c2c2130165.png?v=1710292424","url":"https:\/\/afsbio.com\/products\/angpt1-polyclonal-antibody-e-ab-62625","provider":"AFSBio Inc.","version":"1.0","type":"link"}