{"product_id":"anr28-polyclonal-antibody-bt-ap06288","title":"ANR28 Polyclonal Antibody - BT-AP06288","description":"\u003cp\u003eANR28 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP06288-20, BT-AP06288-50, BT-AP06288-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: Putative regulatory subunit of protein phospatase 6 (PP6) that may be involved in the recognition of phosphoprotein substrates. Involved in the PP6-mediated dephosphorylation of NFKBIE opposing its degradation in response to TNF-alpha. Selectively inhibits the phosphatase activity of PPP1C. Targets PPP1C to modulate HNRPK phosphorylation.,Contains 27 ANK repeats.,subcellular location:Seems to be excluded from nucleoli.,subunit:Protein phospatase 6 (PP6) holoenzyme is proposed to be a heterotrimeric complex formed by the catalytic subunit, a SAPS domain-containing subunit (PP6R) and an ankyrin repeat-domain containing regulatory subunit (ARS). Interacts with PPP1C and HNRPK. Interacts with PPP6C, SAPS1 and SAPS3.,\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cell biology; Epigenetics and nuclear signaling; Signal transduction\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: ANKRD28\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Serine\/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: O15084; Mouse: Q505D1\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: Serine\/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A;PP6-ARS-A;Serine\/threonine-protein phosphatase 6 regulatory subunit ARS-A;Ankyrin repeat domain-containing protein 28;\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 23243\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239051649203,"sku":"BT-AP06288-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239051681971,"sku":"BT-AP06288-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239051714739,"sku":"BT-AP06288-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_cebd09a2-9542-44e8-90df-434dc57eee81.png?v=1769388437","url":"https:\/\/afsbio.com\/products\/anr28-polyclonal-antibody-bt-ap06288","provider":"AFSBio Inc.","version":"1.0","type":"link"}