{"product_id":"anr28-rabbit-pab-es8968","title":"ANR28 rabbit pAb - ES8968","description":"\u003cp\u003eANR28 rabbit pAb\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: ES8968-50, ES8968-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: function:Putative regulatory subunit of protein phospatase 6 (PP6) that may be involved in the recognition of phosphoprotein substrates. Involved in the PP6-mediated dephosphorylation of NFKBIE opposing its degradation in response to TNF-alpha. Selectively inhibits the phosphatase activity of PPP1C. Targets PPP1C to modulate HNRPK phosphorylation., similarity:Contains 27 ANK repeats., subcellular location:Seems to be excluded from nucleoli., subunit:Protein phospatase 6 (PP6) holoenzyme is proposed to be a heterotrimeric complex formed by the catalytic subunit, a SAPS domain-containing subunit (PP6R) and an ankyrin repeat-domain containing regulatory subunit (ARS). Interacts with PPP1C and HNRPK. Interacts with PPP6C, SAPS1 and SAPS3.,\u003c\/p\u003e \n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB; ELISA\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1:500-2000 ELISA 1:5000-20000\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human; Mouse\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthesized peptide derived from human protein . at AA range: 980-1060\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eObserved Band (KD): 115kD\u003c\/p\u003e\n\n\u003cp\u003eHuman Gene ID: 23243\u003c\/p\u003e\n\n\u003cp\u003eHuman SWISS Prot NO: O15084\u003c\/p\u003e\n\n\u003cp\u003eSubcellular Location: Nucleus, nucleoplasm. Seems to be excluded from nucleoli.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ELK Bio","offers":[{"title":"50μL","offer_id":45201672700083,"sku":"ES8968-50","price":207.2,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45201672732851,"sku":"ES8968-100","price":347.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_360x_bbaaf116-1e5f-419a-b5c2-4bf1575288e8.png?v=1767109050","url":"https:\/\/afsbio.com\/products\/anr28-rabbit-pab-es8968","provider":"AFSBio Inc.","version":"1.0","type":"link"}