{"product_id":"ant3-polyclonal-antibody-bt-ap06291","title":"ANT3 Polyclonal Antibody - BT-AP06291","description":"\u003cp\u003eANT3 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP06291-20, BT-AP06291-50, BT-AP06291-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: The protein encoded by this gene is a plasma protease inhibitor and a member of the serpin superfamily. This protein inhibits thrombin as well as other activated serine proteases of the coagulation system, and it regulates the blood coagulation cascade. The protein includes two functional domains: the heparin binding-domain at the N-terminus of the mature protein, and the reactive site domain at the C-terminus. The inhibitory activity is enhanced by the presence of heparin. More than 120 mutations have been identified for this gene, many of which are known to cause antithrombin-III deficiency.\u003c\/p\u003e \n\n\u003cp\u003eResearch Areas: Cardiovascular; Cell biology\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: SERPINC1\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Rat, Mouse\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Antithrombin-III\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: P01008; Mouse: P32261\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: Antithrombin-III;ATIII;Serpin C1\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 462\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239051878579,"sku":"BT-AP06291-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239051911347,"sku":"BT-AP06291-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239051944115,"sku":"BT-AP06291-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_c3e55774-6943-4fa7-9b9f-6595ea812389.png?v=1769388440","url":"https:\/\/afsbio.com\/products\/ant3-polyclonal-antibody-bt-ap06291","provider":"AFSBio Inc.","version":"1.0","type":"link"}