{"product_id":"anti-covid-19-n-protein-mab-igg06fc-bt-cv00001","title":"Anti-Covid-19 N protein mAb IgG(06FC) - BT-CV00001","description":"\u003cp\u003eAnti-Covid-19 N protein mAb IgG(06FC)\u003c\/p\u003e\n\n\u003cp\u003eSizes: 100μg, 1mg\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Number: BT-CV00001-100μg, BT-CV00001-1mg\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: Coronaviruses are enveloped viruses with a positive-sense RNA genome and with a nucleocapsid of helical symmetry. Coronavirus nucleoproteins localize to the cytoplasm and the nucleolus, a subnuclear structure, in both virus-infected primary cells and in cells transfected with plasmids that express N protein. Coronavirus N protein is required for coronavirus RNA synthesis, and has RNA chaperone activity that may be involved in template switch. Nucleocapsid protein is a most abundant protein of coronavirus. During virion assembly, N protein binds to viral RNA and leads to formation of the helical nucleocapsid. Nucleocapsid protein is a highly immunogenic phosphoprotein also implicated in viral genome replication and in modulating cell signaling pathways . Because of the conservation of N protein sequence and its strong immunogenicity, the N protein of coronavirus is chosen as a diagnostic tool. COVID-19 antibodies can be produced by a host immune system following exposure to SARS-CoV-2. IgG and IgM antibodies are also known as immunoglobulins IgG and IgM, respectively, and are among the antibody isotypes produced by vertebrate immune systems.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Others\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: SARS-CoV-2 N, 2019-nCoV N, Covid-19 N\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB,ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Covid-19\u003c\/p\u003e\n\n\u003cp\u003eClonality: Monoclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Mouse\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: SARS-CoV-2 Nucleoprotein , 2019-nCoV Nucleoprotein, Covid-19 Nucleoprotein\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: SARS-CoV-2 Nucleoprotein , 2019-nCoV Nucleoprotein, Covid-19 Nucleoprotein\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"100μg","offer_id":45238351003827,"sku":"BT-CV00001-100μg","price":882.0,"currency_code":"CAD","in_stock":true},{"title":"1mg","offer_id":45238351036595,"sku":"BT-CV00001-1mg","price":2590.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_69dd7519-2c73-4802-bfb8-867458814426.png?v=1769378996","url":"https:\/\/afsbio.com\/products\/anti-covid-19-n-protein-mab-igg06fc-bt-cv00001","provider":"AFSBio Inc.","version":"1.0","type":"link"}