{"product_id":"anti-human-ms4a1-cd3e-bispecific-reference-antibody-glofitamab-ruo-hy257146","title":"Anti-Human MS4A1 \u0026 CD3E Bispecific Reference Antibody (Glofitamab, RUO) - HY257146","description":"\u003cp\u003eAnti-Human MS4A1 \u0026amp; CD3E Bispecific Reference Antibody (Glofitamab, RUO)\u003c\/p\u003e\n\n\u003cp\u003eSizes: 100ug, 1mg\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: HY257146-100, HY257146-1000\u003c\/p\u003e\n\n\u003cp\u003eLead times: 1-2 weeks, if manufacturer has product in stock\u003c\/p\u003e\n\n\u003cp\u003eManufacturer\/Ship Location: China\u003c\/p\u003e\n\n\u003cp\u003eDescription: Glofitamab is a T-cell-engaging bispecific antibody possessing a novel 2:1 structure with bivalency for CD20 on B cells and monovalency for CD3 on T cells. Glofitamab is an investigational, T-cell bispecific antibody with a distinctive design that features 2 Fab arms for binding CD20 on B cells, along with 1 Fab arm for binding CD3 on T cells. The CD3 binding arm is fused directly to one of the CD20-binding arms in a head-to-tail fashion via a short flexible linker.\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eHost: Humanized\u003c\/p\u003e\n\n\u003cp\u003eApplications: ELISA, Bioactivity: FACS, Functional assay\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: Bispecific, CD20-TCB (2:1), RG-6026, 2229047-91-8\u003c\/p\u003e\n\n\u003cp\u003eClonality: Monoclonal\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG1-kappa-lambda\u003c\/p\u003e\n\n\u003cp\u003eTarget: B-lymphocyte surface antigen B1, Membrane-spanning 4-domains subfamily A member 1, MS4A1, Leukocyte surface antigen Leu-16, B-lymphocyte antigen CD20, Bp35, CD20, T3E, T-cell surface antigen T3\/Leu-4 epsilon chain, CD3e, CD3E, T-cell surface glycoprotein CD3 epsilon chain\u003c\/p\u003e\n\n\u003cp\u003ePurification: Protein A\/G purified from cell culture supernatant.\u003c\/p\u003e\n\n\u003cp\u003ePurity: \u0026gt;95% as determined by SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eExpression System: Mammalian Cells\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.\u003c\/p\u003e\n\n\u003cp\u003eStorage Buffer: 0.01M PBS, pH 7.4.\u003c\/p\u003e\n\n\u003cp\u003eForm: Liquid\u003c\/p\u003e\n\n\u003cp\u003eAccession: P11836 \u0026amp; P07766\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin Level: Contact Us for more information.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"abinScience","offers":[{"title":"100μg","offer_id":46155514740915,"sku":"HY257146-100","price":330.0,"currency_code":"CAD","in_stock":true},{"title":"1mg","offer_id":46155514773683,"sku":"HY257146-1000","price":723.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/Abinscience_logo_for_products.jpg?v=1790954517","url":"https:\/\/afsbio.com\/products\/anti-human-ms4a1-cd3e-bispecific-reference-antibody-glofitamab-ruo-hy257146","provider":"AFSBio Inc.","version":"1.0","type":"link"}