{"product_id":"anti-mers-cov-nucleocapsid-monoclonal-antibody-e-ab-v1281","title":"Anti-MERS-CoV Nucleocapsid Monoclonal Antibody - E-AB-V1281","description":"\u003cp\u003eAnti-MERS-CoV Nucleocapsid Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-V1281-50, E-AB-V1281-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: coronavirus NP; coronavirus Nucleocapsid; coronavirus Nucleoprotein; cov np; ncov NP; novel coronavirus Nucleoprotein; NP; Nucleocapsid; Nucleoprotein\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Mouse\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: MERS-CoV\u003c\/p\u003e\n\n\u003cp\u003eApplication: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG1\u003c\/p\u003e\n\n\u003cp\u003eClonality: Monoclonal\u003c\/p\u003e\n\n\u003cp\u003eClone No.: 10\u003c\/p\u003e\n\n\u003cp\u003eBackground: Coronaviruses are enveloped viruses with a positive-sense RNA genome and with a nucleocapsid of helical symmetry. Coronavirus nucleoproteins localize to the cytoplasm and the nucleolus, a subnuclear structure, in both virus-infected primary cells and in cells transfected with plasmids that express N protein. Coronavirus N protein is required for coronavirus RNA synthesis, and has RNA chaperone activity that may be involved in template switch. Nucleocapsid protein is a most abundant protein of coronavirus. During virion assembly, N protein binds to viral RNA and leads to formation of the helical nucleocapsid. Nucleocapsid protein is a highly immunogenic phosphoprotein also implicated in viral genome replication and in modulating cell signaling pathways. Because of the conservation of N protein sequence and its strong immunogenicity, the N protein of coronavirus is chosen as a diagnostic tool.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant MERS-CoV Nucleoprotein \/ NP protein (His Tag)\u003c\/p\u003e\n\n\u003cp\u003eBuffer: 0.2 μm filtered solution in PBS\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Protein A Affinity\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1:1000-1:5000\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"50μL","offer_id":43149015220403,"sku":"E-AB-V1281-50","price":350.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":43149015253171,"sku":"E-AB-V1281-100","price":581.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_ae1d4f8c-1266-4f95-b4d8-173753161368.png?v=1710338215","url":"https:\/\/afsbio.com\/products\/anti-mers-cov-nucleocapsid-monoclonal-antibody-e-ab-v1281","provider":"AFSBio Inc.","version":"1.0","type":"link"}