{"product_id":"anti-ramucirumab-polyclonal-antibody-aw338014","title":"Anti-Ramucirumab Polyclonal Antibody - AW338014","description":"\u003cp\u003eAnti-Ramucirumab Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μg, 100μg\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: AW338014-50, AW338014-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eHost species: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: The product is specific for Ramucirumab. This antibody serves as an excellent positive control for Ramucirumab immunogenicity (ADA) assays.\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Ramucirumab\u003c\/p\u003e\n\n\u003cp\u003eForm: Liquid\u003c\/p\u003e\n\n\u003cp\u003eStorage buffer: 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eApplications: ELISA\u003c\/p\u003e\n\n\u003cp\u003ePurification: Antigen affinity purification.\u003c\/p\u003e\n\n\u003cp\u003eStability and Storage: The product can be stored for 2-3 weeks at 2-8°C or for up to 12 months at -20°C. Avoid repeated freezing and thawing cycles.\u003c\/p\u003e\n\n\u003cp\u003eBackground: Ramucirumab (LY3009806) is a human monoclonal antibody (IgG1) against vascular endothelial growth factor receptor 2 (VEGFR2), a type II trans-membrane tyrosine kinase receptor expressed on endothelial cells. By binding to VEGFR2, ramucirumab prevents binding of its ligands (VEGF-A, VEGF-C, and VEGF-D), thereby preventing VEGF-stimulated receptor phosphorylation and downstream ligand-induced proliferation, permeability, and migration of human endothelial cells.\u003c\/p\u003e\n\n\u003cp\u003eAlternative Names: Rabbit polyclonal to REGN-10987.\u003c\/p\u003e\n\n\u003cp\u003eAntibodysystem can customize this product per customer's request including product size, buffer components, etc. For research use only.\u003c\/p\u003e","brand":"abinScience","offers":[{"title":"50μg","offer_id":45357908852915,"sku":"AW338014-50","price":492.8,"currency_code":"CAD","in_stock":true},{"title":"100μg","offer_id":45357908885683,"sku":"AW338014-100","price":949.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/abinscience.png?v=1773676488","url":"https:\/\/afsbio.com\/products\/anti-ramucirumab-polyclonal-antibody-aw338014","provider":"AFSBio Inc.","version":"1.0","type":"link"}