{"product_id":"antxr1-polyclonal-antibody-bs71922","title":"ANTXR1 Polyclonal Antibody-BS71922","description":"\u003cp\u003eANTXR1 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eProduct: Rabbit IgG, 1mg\/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BS71922-50, BS71922-100\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: Q9H6X2\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eANTXR1 Polyclonal Antibody-BS71922\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IF\u003c\/p\u003e\n\n\u003cp\u003eAll Applications: WB\t1:500 - 1:2000\u003cbr\u003e\nIF\t1:50 - 1:100\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a type I transmembrane protein and is a tumor-specific endothelial marker that has been implicated in colorectal cancer. The encoded protein has been shown to also be a docking protein or receptor for Bacillus anthracis toxin, the causative agent of the disease, anthrax. The binding of the protective antigen (PA) component, of the tripartite anthrax toxin, to this receptor protein mediates delivery of toxin components to the cytosol of cells. Once inside the cell, the other two components of anthrax toxin, edema factor (EF) and lethal factor (LF) disrupt normal cellular processes. Three alternatively spliced variants that encode different protein isoforms have been described.\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is \u0026gt; 95% (by SDS-PAGE).\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: ANTXR1 polyclonal antibody detects endogenous levels of ANTXR1 protein.\u003c\/p\u003e\n\n\u003cp\u003eBioworld Molecular Weight: 75kDa\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Western blot analysis of extracts of various cell lines, using ANTXR1 antibody at 1:1000 dilution., Immunofluorescence analysis of HeLa cell using ANTXR1 antibody. Blue: DAPI for nuclear staining.\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: ATR; GAPO; TEM8\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant protein of human ANTXR1\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42962815484083,"sku":"BS71922-50","price":342.59,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42962815516851,"sku":"BS71922-100","price":589.65,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_8009c5da-a067-434d-a85f-90b146333af9.jpg?v=1705319098","url":"https:\/\/afsbio.com\/products\/antxr1-polyclonal-antibody-bs71922","provider":"AFSBio Inc.","version":"1.0","type":"link"}