{"product_id":"ap1m2-rabbit-polyclonal-antibody-es18311","title":"AP1M2 Rabbit Polyclonal Antibody - ES18311","description":"\u003cp\u003eAP1M2 Rabbit Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: ES18311-50, ES18311-100\u003c\/p\u003e\n\n\u003cp\u003eLead times: 1-2 weeks, if manufacturer has product in stock\u003c\/p\u003e\n\n\u003cp\u003eManufacturer\/Ship Location: China\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a subunit of the heterotetrameric adaptor-related protein comlex 1 (AP-1), which belongs to the adaptor complexes medium subunits family. This protein is capable of interacting with tyrosine-based sorting signals. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014],\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthesized peptide derived from human AP1M2 AA range: 117-167\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eTarget: AP1M2\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: This antibody detects endogenous levels of AP1M2 at Human\/Mouse\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1：500-2000\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml,\u003c\/p\u003e\n\n\u003cp\u003eFormlation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 47kD\u003c\/p\u003e\n\n\u003cp\u003eFields: Lysosome, Human immunodeficiency virus 1 infection\u003c\/p\u003e\n\n\u003cp\u003eFunction: Function: Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules\u003cbr\u003e\nPTM: Phosphorylation of membrane-bound AP1M1\/AP1M2 increases its affinity for sorting signals\u003cbr\u003e\nSimilarity: Belongs to the adaptor complexes medium subunit family\u003cbr\u003e\nSimilarity: Contains 1 MHD (mu homology) domain\u003cbr\u003e\nSubcellular Location: Component of the coat surrounding the cytoplasmic face of coated vesicles located at the Golgi complex\u003cbr\u003e\nSubunit: Adaptor protein complex 1 (AP-1) is an heterotetramer composed of two large adaptins (gamma-type subunit AP1G1 and beta-type subunit AP1B1), a medium adaptin (mu-type subunit AP1M1 or AP1M2) and a small adaptin (sigma-type subunit AP1S1 or A\u003c\/p\u003e\n\n\u003cp\u003eSubcellular Location: Golgi apparatus Cytoplasmic vesicle, clathrin-coated vesicle membrane, Peripheral membrane protein, Cytoplasmic side Component of the coat surrounding the cytoplasmic face of coated vesicles located at the Golgi complex\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eGene Name: AP1M2\u003c\/p\u003e\n\n\u003cp\u003eProtein Name: AP1M2\u003c\/p\u003e\n\n\u003cp\u003eMouse Gene ID: 11768\u003c\/p\u003e\n\n\u003cp\u003eMouse SwissProt Number: Q9WVP1\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ELK Biotechnology","offers":[{"title":"50μL","offer_id":46315801772211,"sku":"ES18311-50","price":186.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":46315801804979,"sku":"ES18311-100","price":372.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/elk_antibodies.jpg?v=1793190497","url":"https:\/\/afsbio.com\/products\/ap1m2-rabbit-polyclonal-antibody-es18311","provider":"AFSBio Inc.","version":"1.0","type":"link"}