{"product_id":"apc-anti-human-cd180-antibody-mhr73-11-apc-30283","title":"APC Anti-Human CD180 Antibody (MHR73-11) - APC-30283","description":"\u003cp\u003eAPC Anti-Human CD180 Antibody (MHR73-11)\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20T, 100T\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: APC-30283-20, APC-30283-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eTarget: Human CD180\u003c\/p\u003e\n\n\u003cp\u003eForm: Liquid\u003c\/p\u003e\n\n\u003cp\u003eConjugation: APC\u003c\/p\u003e\n\n\u003cp\u003eConjugation Information: APC is designed to be excited by the Red (627-640 nm) laser and detected using an optical filter centered near 660 nm (e.g., a 660\/20 nm bandpass filter).\u003c\/p\u003e\n\n \n\n \n\n\n\n\u003cp\u003eHost: Mouse\u003c\/p\u003e\n\n\u003cp\u003eClonality: Monoclonal\u003c\/p\u003e\n\n\u003cp\u003eClone ID: MHR73-11\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG1, κ\u003c\/p\u003e\n\n\u003cp\u003eStorage: PBS with 0. 1% sodium azide, 1%BSA, pH 7.3, 2-8℃ for 12 months (Avoid repeated freeze \/ thaw cycles.)\u003c\/p\u003e\n\n\u003cp\u003eBackground: CD180, also known as RP105, is a 105 kD member of the toll-like receptor (TLR) family and is expressed on most B cells, monocytes\/macrophages and dendritic cells. The TLR family's structural characteristics are critically involved in protein-protein signaling interactions leading to the activation of the innate immune system. Additionally, MD-1, a secretory protein, associates with CD180 (RP105) at the cell surface and this complex, in conjunction with TLR4, recognizes bacterial LPS. The human CD180 (RP105) gene maps to 5q12. The MHR73-11 Antibody is able to activate B cells and to protect against irradiation- or dexamethasone-induced apoptosis.\u003c\/p\u003e\n\n \n\n\u003cp\u003eSynonyms: CD180|Radio-protective 105-kD protein|RP105\u003c\/p\u003e\n\n \n\n\u003cp\u003eUniprot ID: Q99467\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eTested Application: FC\u003c\/p\u003e\n\n\u003cp\u003eRecommended Dilution: Volume per test: 5μL. Each lot of this antibody is quality control tested by Flow cytometryometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.\u003c\/p\u003e\n\n\u003cp\u003eGene ID: 4064\u003c\/p\u003e\n\n \n\n \n\n\u003cp\u003eCategory: Flow cytometryometry Antibodies\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Fine Biotech","offers":[{"title":"20T","offer_id":45346326544563,"sku":"APC-30283-20","price":386.4,"currency_code":"CAD","in_stock":true},{"title":"100T","offer_id":45346326577331,"sku":"APC-30283-100","price":767.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/FineTest_Logo.png?v=1781809832","url":"https:\/\/afsbio.com\/products\/apc-anti-human-cd180-antibody-mhr73-11-apc-30283","provider":"AFSBio Inc.","version":"1.0","type":"link"}