{"product_id":"apc-anti-human-cd193-ccr3-antibody-5e8-e-ab-f1303e","title":"APC Anti-Human CD193\/CCR3 Antibody [5E8] - E-AB-F1303E","description":"\u003cp\u003eAPC Anti-Human CD193\/CCR3 Antibody [5E8]\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20 Tests, 100 Tests, 100 Tests×2\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-F1303E-20, E-AB-F1303E-100, E-AB-F1303E-100×2\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: CD193\/CCR3\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: CC CKR3,  MIP1-alpha receptor like-2,  eotaxin receptor, CCR, C-C chemokine receptor type 3,\u003c\/p\u003e \n\n\u003cp\u003eConjugation: APC\u003c\/p\u003e\n\n\u003cp\u003eHost: Mouse\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eApplication: FCM\u003c\/p\u003e\n\n\u003cp\u003eUsage: Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.\u003c\/p\u003e\n\n\u003cp\u003eIsotype: Mouse IgG2b, κ\u003c\/p\u003e\n\n\u003cp\u003eClone No.: 500000000\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: P51677\u003c\/p\u003e\n\n\u003cp\u003eBackground: CD193, also known as CC-chemokine receptor 3 (CCR3), CC CKR3, MIP1-alpha receptor like-2, and eotaxin receptor, is a member of the G protein-coupled seven transmembrane receptors family. It binds to the CC chemokines eotaxin, eotaxin-2, and eotaxin-3 with high affinity. CCR3 has also been reported to bind RANTES, MCP-3, and MCP-4 with low affinity. CCR3 receptor is expressed on human eosinophils, basophils, mast cells, mononuclear phagocytes, platelets, CD34+ hematopoietic progenitor cells, Th2-like lymphocytes, and keratinocytes. CCR3 is thought to play a role in allergic diseases such as bronchial asthma and allergic rhinitis. CCR3 is a co-receptor for HIV-1 and HIV-2, and the binding of eotaxin with CCR3 has been shown to inhibit HIV infection in some cell types.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 5 μL\/Test\u003c\/p\u003e\n\n\u003cp\u003eControl Catalogue Number: E-AB-F09812E\u003c\/p\u003e\n\n\u003cp\u003eBuffer: Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 1232\u003c\/p\u003e\n\n\u003cp\u003eStorage: This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"20 Tests","offer_id":43157036073139,"sku":"E-AB-F1303E-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"100 Tests","offer_id":43157036105907,"sku":"E-AB-F1303E-100","price":403.2,"currency_code":"CAD","in_stock":true},{"title":"100 Tests×2","offer_id":43157036138675,"sku":"E-AB-F1303E-100×2","price":604.8,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_9c82f066-be19-45e9-bcec-ccdb97de056a.png?v=1710508519","url":"https:\/\/afsbio.com\/products\/apc-anti-human-cd193-ccr3-antibody-5e8-e-ab-f1303e","provider":"AFSBio Inc.","version":"1.0","type":"link"}