{"product_id":"apc-anti-human-cd45-antibody-hi30-e-ab-f1137e","title":"APC Anti-Human CD45 Antibody [HI30] - E-AB-F1137E","description":"\u003cp\u003eAPC Anti-Human CD45 Antibody [HI30]\u003c\/p\u003e\n\n\u003cp\u003eSize: 100Tests×2\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Number: E-AB-F1137E-100×2\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: CD45\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: Receptor-type tyrosine-protein phosphatase C, Ptprc, L-CA, Ly-5, T200, CD45,\u003c\/p\u003e \n\n\u003cp\u003eConjugation: APC\u003c\/p\u003e\n\n\u003cp\u003eHost: Mouse\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eApplication: FCM\u003c\/p\u003e\n\n\u003cp\u003eUsage: Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.\u003c\/p\u003e\n\n\u003cp\u003eIsotype: Mouse IgG1, κ\u003c\/p\u003e\n\n\u003cp\u003eClone No.: HI30\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: P08575\u003c\/p\u003e\n\n\u003cp\u003eBackground: CD45 is a 180 - 240 kD single chain type I membrane glycoprotein also known as leukocyte common antigen (LCA) and T200. It is a tyrosine phosphatase expressed on the plasma membrane of all hematopoietic cells, except erythrocytes or platelets. CD45 is a signaling molecule that regulates a variety of cellular processes including cell growth, differentiation, cell cycle, and oncogenic transformation. CD45 plays a critical role in T and B cell antigen receptor-mediated activation by dephosphorylating substrates including p56Lck, p59Fyn, and other Src family kinases. CD45 non-covalently associates with lymphocyte phosphatase-associated phosphoprotein (LPAP) on T and B lymphocytes. CD45 has been reported to bind galectin-1 and to be associated with several other cell surface antigens including CD1, CD2, CD3, and CD4.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 5 μL\/Test\u003c\/p\u003e\n\n\u003cp\u003eControl Catalogue Number: E-AB-F09792E\u003c\/p\u003e\n\n\u003cp\u003eBuffer: Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 5788\u003c\/p\u003e\n\n\u003cp\u003eStorage: This product can be stored at 2-8°C for 12 months. Please protect from prolonged exposure to light and do not freeze.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"100Tests×2","offer_id":43157409792179,"sku":"E-AB-F1137E-100×2","price":189.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_c16010bd-48df-4fad-b219-fb888cd0a655.png?v=1710514362","url":"https:\/\/afsbio.com\/products\/apc-anti-human-cd45-antibody-hi30-e-ab-f1137e","provider":"AFSBio Inc.","version":"1.0","type":"link"}