{"product_id":"apc-anti-mouse-cd107a-lamp-1-antibody-1d4b-e-ab-f1254e","title":"APC Anti-Mouse CD107a\/LAMP-1 Antibody [1D4B] - E-AB-F1254E","description":"\u003cp\u003eAPC Anti-Mouse CD107a\/LAMP-1 Antibody [1D4B]\u003c\/p\u003e\n\n\u003cp\u003eSizes: 100 Tests, 100 Tests×2\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-F1254E-100, E-AB-F1254E-100×2\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: CD107a\/LAMP-1\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: LAMP-1, Lysosome-associated membrane glycoprotein 1, lysosomal membrane glycoprotein 1, CD107 antigen-like family member A, lysosome-associated membrane protein 1,\u003c\/p\u003e \n\n\u003cp\u003eConjugation: APC\u003c\/p\u003e\n\n\u003cp\u003eHost: Rat\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Mouse\u003c\/p\u003e\n\n\u003cp\u003eApplication: FCM\u003c\/p\u003e\n\n\u003cp\u003eUsage: Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.\u003c\/p\u003e\n\n\u003cp\u003eIsotype: Rat IgG2a, κ\u003c\/p\u003e\n\n\u003cp\u003eClone No.: 1D4B\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: P11438\u003c\/p\u003e\n\n\u003cp\u003eBackground: The 1D4B antibody recognizes CD107a which is also known as, Lysosome-Associated Membrane Protein 1 (LAMP-1). CD107a is one of the two major glycoproteins in lysosome membranes that provide useful markers to distinguish lysosomes from other organelles. CD107a may play a role in the lysosomal degradation of certain molecules. Mouse CD107a is a type I transmembrane glycoprotein. It consists of a 40-kDa core protein which is heavily glycosylated to form heterogeneous mature glycoprotein of 110-140 kDa. It is principally expressed in epithelial cells and macrophages in a variety of organs. Following activation, CD107a is relocated to the surface of some lymphocytes, macrophages, epithelial cells, endothelial cells, platelets, and tumor cells. Cell-surface CD107a may participate in intercellular adhesion and adhesion to the extracellular matrix. Cell surface CD107a expression can serve as a useful marker for cytotoxic NK and CD8+ T cells, as well as, some malignant tumor cells.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 5 μL\/Test\u003c\/p\u003e\n\n\u003cp\u003eControl Catalogue Number: E-AB-F09832E\u003c\/p\u003e\n\n\u003cp\u003eBuffer: Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.\u003c\/p\u003e\n\n\u003cp\u003eGene ID: 16783\u003c\/p\u003e\n\n\u003cp\u003eStorage: This product can be stored at 2-8°C for 12 months. Please protect from prolonged exposure to light and do not freeze.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"100 Tests","offer_id":43157206532275,"sku":"E-AB-F1254E-100","price":168.0,"currency_code":"CAD","in_stock":true},{"title":"100 Tests×2","offer_id":43157206565043,"sku":"E-AB-F1254E-100×2","price":268.8,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_7683e0f4-eb86-488a-8be3-ca1149974161.png?v=1710512256","url":"https:\/\/afsbio.com\/products\/apc-anti-mouse-cd107a-lamp-1-antibody-1d4b-e-ab-f1254e","provider":"AFSBio Inc.","version":"1.0","type":"link"}