{"product_id":"apc-anti-mouse-cd119-antibody-gr-20-e-ab-f1115e","title":"APC Anti-Mouse CD119 Antibody [GR-20] - E-AB-F1115E","description":"\u003cp\u003eAPC Anti-Mouse CD119 Antibody [GR-20]\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50 Tests, 100 Tests, 100 Tests×2\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-F1115E-50, E-AB-F1115E-100, E-AB-F1115E-100×2\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: CD119\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: Interferon gamma receptor 1, Ifngr1, IFN-gamma-R1, IFN-gamma-R-alpha, CD119,\u003c\/p\u003e \n\n\u003cp\u003eConjugation: APC\u003c\/p\u003e\n\n\u003cp\u003eMouse\u003c\/p\u003e\n\n\u003cp\u003eApplication: FCM\u003c\/p\u003e\n\n\u003cp\u003eUsage: Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.\u003c\/p\u003e\n\n\u003cp\u003eIsotype: Rat IgG2a, κ\u003c\/p\u003e\n\n\u003cp\u003eClone No.: GR-20\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: P15261\u003c\/p\u003e\n\n\u003cp\u003eBackground: CDw119 is a 90 kD immunoglobulin superfamily member, also known as IFN-γRα chain. It is a class II cytokine receptor family member that serves as a IFN-γ-binding chain associated with the IFN-γ β chain also known as AF-1. In addition to ligand binding, CDw119 participates in ligand trafficking. CDw119 is expressed on T and B cells, NK cells, fibroblasts, endothelial, and epithelial cells. Binding of IFN-γ induces receptor dimerization, internalization, Jak1 and Jak2 protein kinase activation and, ultimately, STAT1 activation. IFN-γ initiates and regulates a variety of immune responses.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 5 μL\/Test\u003c\/p\u003e\n\n\u003cp\u003eControl Catalogue Number: E-AB-F09832E\u003c\/p\u003e\n\n\u003cp\u003eBuffer: Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 15979\u003c\/p\u003e\n\n\u003cp\u003eStorage: This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"50 Tests","offer_id":43157043478707,"sku":"E-AB-F1115E-50","price":172.2,"currency_code":"CAD","in_stock":true},{"title":"100 Tests","offer_id":43157043511475,"sku":"E-AB-F1115E-100","price":261.8,"currency_code":"CAD","in_stock":true},{"title":"100 Tests×2","offer_id":43157043544243,"sku":"E-AB-F1115E-100×2","price":462.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_8bdbb9c6-bbbd-4e07-b8e6-191b3b878d10.png?v=1710508692","url":"https:\/\/afsbio.com\/products\/apc-anti-mouse-cd119-antibody-gr-20-e-ab-f1115e","provider":"AFSBio Inc.","version":"1.0","type":"link"}