{"product_id":"apc-anti-mouse-cd161-nk1-1-antibody-pk136-e-ab-f0987ue","title":"APC Anti-Mouse CD161\/NK1.1 Antibody [PK136] - E-AB-F0987UE","description":"\u003cp\u003eAPC Anti-Mouse CD161\/NK1.1 Antibody [PK136]\u003c\/p\u003e\n\n\u003cp\u003eSize: 100μg\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Number: E-AB-F0987UE-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: CD161\/NK1.1\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: Killer cell lectin-like receptor subfamily B member 1C, Klrb1c, CD161 antigen-like family member C, Ly-55c, CD161\/NK1.1, NKR-P1.9, NKR-P1C, NKR-P1 40, CD161c,\u003c\/p\u003e \n\n\u003cp\u003eConjugation: APC\u003c\/p\u003e\n\n\u003cp\u003eHost: Mouse\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Mouse\u003c\/p\u003e\n\n\u003cp\u003eApplication: FCM\u003c\/p\u003e\n\n\u003cp\u003eUsage: Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg\/10^6 cells in 100 μL volume].\u003c\/p\u003e\n\n\u003cp\u003eIsotype: Mouse IgG2a, κ\u003c\/p\u003e\n\n\u003cp\u003eClone No.: PK136\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: P27814, P27812, Q99JB4,\u003c\/p\u003e \n\n\u003cp\u003eBackground: NK-1.1 surface antigen, also known as CD161b\/CD161c and Ly-55, is encoded by the NKR-P1B\/NKR-P1C gene. It is expressed on NK cells and NK-T cells in some mouse strains, including C57BL\/6, FVB\/N, and NZB, but not AKR, BALB\/c, CBA\/J, C3H, DBA\/1, DBA\/2, NOD, SJL, and 129. Expression of NKR-P1C antigen has been correlated with lysis of tumor cells in vitro and rejection of bone marrow allografts in vivo. NK-1.1 has also been shown to play a role in NK cell activation, IFN-γ production, and cytotoxic granule release. NK-1.1 and DX5 are commonly used as mouse NK cell markers.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 0.2 mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eControl Catalogue Number: E-AB-F09803E\u003c\/p\u003e\n\n\u003cp\u003eBuffer: Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 17059\u003c\/p\u003e\n\n\u003cp\u003eStorage: This product can be stored at 2-8°C for 12 months. Please protect from prolonged exposure to light and do not freeze.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"100μg","offer_id":43157291827379,"sku":"E-AB-F0987UE-100","price":369.6,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_e4a52ddc-3abe-43fb-8d41-f78332242865.png?v=1710513161","url":"https:\/\/afsbio.com\/products\/apc-anti-mouse-cd161-nk1-1-antibody-pk136-e-ab-f0987ue","provider":"AFSBio Inc.","version":"1.0","type":"link"}