{"product_id":"apc-anti-mouse-cd366-tim-3-antibody-rmt3-23-e-ab-f1192e","title":"APC Anti-Mouse CD366\/Tim-3 Antibody [RMT3-23] - E-AB-F1192E","description":"\u003cp\u003eAPC Anti-Mouse CD366\/Tim-3 Antibody [RMT3-23]\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50 Tests, 100 Tests, 100 Tests×2\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-F1192E-50, E-AB-F1192E-100, E-AB-F1192E-100×2\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: CD366\/Tim-3\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: TIM3,  TIMD3, HAVcr-2, TIMD-3,\u003c\/p\u003e \n\n\u003cp\u003eConjugation: APC\u003c\/p\u003e\n\n\u003cp\u003eHost: Rat\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Mouse\u003c\/p\u003e\n\n\u003cp\u003eApplication: FCM\u003c\/p\u003e\n\n\u003cp\u003eUsage: Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.\u003c\/p\u003e\n\n\u003cp\u003eIsotype: Rat IgG2a, κ\u003c\/p\u003e\n\n\u003cp\u003eClone No.: RMT3-23\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: Q8VIM0\u003c\/p\u003e\n\n\u003cp\u003eBackground: CD366 (Tim-3) is a transmembrane protein also known as T cell immunoglobulin and mucin domain containing protein-3. Tim-3 is expressed at high levels on activated T cells (preferentially on Th1 cells, monocytes\/macrophages, and dendritic cells). Tim-3 has also been shown to exist as a soluble protein. Cells expressing Tim-3 are present at high levels in the CNS of animals at the onset of experimental autoimmune encephalomyelitis (EAE), a disease mediated by lymphocytes secreting Th1-like cytokines. Tim-3 has been proposed to inhibit Th1-mediated immune responses and promote immunological tolerance.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 5 μL\/Test\u003c\/p\u003e\n\n\u003cp\u003eControl Catalogue Number: E-AB-F09832E\u003c\/p\u003e\n\n\u003cp\u003eBuffer: Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 84868\u003c\/p\u003e\n\n\u003cp\u003eStorage: This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"50 Tests","offer_id":43157029552307,"sku":"E-AB-F1192E-50","price":172.2,"currency_code":"CAD","in_stock":true},{"title":"100 Tests","offer_id":43157029585075,"sku":"E-AB-F1192E-100","price":261.8,"currency_code":"CAD","in_stock":true},{"title":"100 Tests×2","offer_id":43157029617843,"sku":"E-AB-F1192E-100×2","price":462.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_6307873f-b4d5-4225-baa2-0e3f8290dac5.png?v=1710508364","url":"https:\/\/afsbio.com\/products\/apc-anti-mouse-cd366-tim-3-antibody-rmt3-23-e-ab-f1192e","provider":"AFSBio Inc.","version":"1.0","type":"link"}