{"product_id":"apc-anti-mouse-cd40-antibody-fgk4-5-fgk45-e-ab-f1028e","title":"APC Anti-Mouse CD40 Antibody [FGK4.5\/FGK45] - E-AB-F1028E","description":"\u003cp\u003eAPC Anti-Mouse CD40 Antibody [FGK4.5\/FGK45]\u003c\/p\u003e\n\n\u003cp\u003eSizes: 100 Tests, 100 Tests×2\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-F1028E-100, E-AB-F1028E-100×2\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: CD40\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: Tumor necrosis factor receptor superfamily member 5, Cd40, B-cell surface antigen CD40, Bp50, CD40L receptor, CD40, Tnfrsf5,\u003c\/p\u003e \n\n\u003cp\u003eConjugation: APC\u003c\/p\u003e\n\n\u003cp\u003eHost: Rat\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Mouse\u003c\/p\u003e\n\n\u003cp\u003eApplication: FCM\u003c\/p\u003e\n\n\u003cp\u003eUsage: Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.\u003c\/p\u003e\n\n\u003cp\u003eIsotype: Rat IgG2a, κ\u003c\/p\u003e\n\n\u003cp\u003eClone No.: FGK4.5\/FGK45\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: P27512\u003c\/p\u003e\n\n\u003cp\u003eBackground: CD40 is a 48 kD type I transmembrane glycoprotein also known as Bp50. It is a member of the tumor necrosis factor receptor (TNFR) superfamily and is expressed on B cells, basal epithelial cells, macrophages, follicular dendritic cells, endothelial cells, and a subset of CD34+ hematopoietic progenitors. CD40 regulates B cell development\/maturation, Ig isotype switching and, in combination with other signals such as IL-4, protects B cells from surface Ig-induced apoptosis and promotes proliferation. Interaction of CD40 with its ligand CD154 (gp39), which is expressed on activated T cells, is important in costimulation and immune regulation.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 5 μL\/Test\u003c\/p\u003e\n\n\u003cp\u003eControl Catalogue Number: E-AB-F09832E\u003c\/p\u003e\n\n\u003cp\u003eBuffer: Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.\u003c\/p\u003e\n\n\u003cp\u003eGene ID: 21939\u003c\/p\u003e\n\n\u003cp\u003eStorage: This product can be stored at 2-8°C for 12 months. Please protect from prolonged exposure to light and do not freeze.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"100 Tests","offer_id":43157084012723,"sku":"E-AB-F1028E-100","price":140.0,"currency_code":"CAD","in_stock":true},{"title":"100 Tests×2","offer_id":43157084045491,"sku":"E-AB-F1028E-100×2","price":224.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_4a6c0e88-5b2a-4d4f-b75d-83ff41c89dc1.png?v=1710510583","url":"https:\/\/afsbio.com\/products\/apc-anti-mouse-cd40-antibody-fgk4-5-fgk45-e-ab-f1028e","provider":"AFSBio Inc.","version":"1.0","type":"link"}