{"product_id":"apc-anti-mouse-cd45r-b220-antibody-ra3-3a-1-6-1-e-ab-f1112e","title":"APC Anti-Mouse CD45R\/B220 Antibody [RA3.3A 1\/6.1] - E-AB-F1112E","description":"\u003cp\u003eAPC Anti-Mouse CD45R\/B220 Antibody [RA3.3A 1\/6.1]\u003c\/p\u003e\n\n\u003cp\u003eSize: 100Tests×2\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Number: E-AB-F1112E-100×2\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: CD45R\/B220\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: B220,\u003c\/p\u003e \n\n\u003cp\u003eConjugation: APC\u003c\/p\u003e\n\n\u003cp\u003eHost: Rat\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Mouse\u003c\/p\u003e\n\n\u003cp\u003eApplication: FCM\u003c\/p\u003e\n\n\u003cp\u003eUsage: Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.\u003c\/p\u003e\n\n\u003cp\u003eIsotype: Rat IgM, κ\u003c\/p\u003e\n\n\u003cp\u003eClone No.: RA3.3A 1\/6.1\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: ???\u003c\/p\u003e\n\n\u003cp\u003eBackground: CD45R, also known as B220, is an isoform of CD45. It is a member of the protein tyrosine phosphatase (PTP) family with a molecular weight of approximately 180-240 kD. CD45R is expressed on B cells (at all developmental stages from pro-B cells through mature B cells), activated B cells, and subsets of T and NK cells. CD45R (B220) is also expressed on a subset of abnormal T cells involved in the pathogenesis of systemic autoimmunity in MRL-Faslpr and MRL-Fasgld mice. It plays a critical role in TCR and BCR signaling. The primary ligands for CD45 are galectin-1, CD2, CD3, and CD4. CD45R is commonly used as a pan-B cell marker, however, CD19 may be more appropriate for B cell specificity.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 5 μL\/Test\u003c\/p\u003e\n\n\u003cp\u003eControl Catalogue Number: E-AB-F09772E\u003c\/p\u003e\n\n\u003cp\u003eBuffer: Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 192, 645, 788\u003c\/p\u003e\n\n\u003cp\u003eStorage: This product can be stored at 2-8°C for 12 months. Please protect from prolonged exposure to light and do not freeze.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"100Tests×2","offer_id":43157270659251,"sku":"E-AB-F1112E-100×2","price":175.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_4971e20c-4280-4bbe-9321-2390618b8b07.png?v=1710512906","url":"https:\/\/afsbio.com\/products\/apc-anti-mouse-cd45r-b220-antibody-ra3-3a-1-6-1-e-ab-f1112e","provider":"AFSBio Inc.","version":"1.0","type":"link"}