{"product_id":"apc-anti-mouse-cd62l-antibody-mel14-e-ab-f1011ue","title":"APC Anti-Mouse CD62L Antibody [Mel14] - E-AB-F1011UE","description":"\u003cp\u003eAPC Anti-Mouse CD62L Antibody [Mel14]\u003c\/p\u003e\n\n\u003cp\u003eSize: 100μg\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Number: E-AB-F1011UE-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: CD62L\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: L-selectin, Sell, CD62 antigen-like family member L, LAM-1, LECAM1, Lymph node homing receptor, Ly-22, CD62L, Lnhr, Ly22,\u003c\/p\u003e \n\n\u003cp\u003eConjugation: APC\u003c\/p\u003e\n\n\u003cp\u003eHost: Rat\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Mouse\u003c\/p\u003e\n\n\u003cp\u003eApplication: FCM\u003c\/p\u003e\n\n\u003cp\u003eUsage: Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg\/10^6 cells in 100 μL volume].\u003c\/p\u003e\n\n\u003cp\u003eIsotype: Rat IgG2a, κ\u003c\/p\u003e\n\n\u003cp\u003eClone No.: Mel14\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: P18337\u003c\/p\u003e\n\n\u003cp\u003eBackground: CD62L is a 74-95 kD glycoprotein also known as L-selectin, LECAM-1, Ly-22, LAM-1, and MEL-14. It is a member of the selectin family and is expressed on the majority of B and naive T cells, a subset of memory T cells, monocytes, granulocytes, most thymocytes, and a subset of NK cells. CD62L is important in lymphocyte homing to high endothelial venules (HEV) in peripheral lymph nodes and leukocyte 'rolling' on activated endothelium. CD62L also contributes to neutrophil emigration at inflammatory sites. CD62L is rapidly shed from lymphocytes and neutrophils upon cellular activation and the expression levels of CD62L (in conjunction with other markers) have been used to distinguish naive, effector, and memory T cells. CD62L has been reported to interact with CD34, GlyCAM-1, and MAdCAM-1.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 0.2 mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eControl Catalogue Number: E-AB-F09833E\u003c\/p\u003e\n\n\u003cp\u003eBuffer: Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 20343\u003c\/p\u003e\n\n\u003cp\u003eStorage: This product can be stored at 2-8°C for 12 months. Please protect from prolonged exposure to light and do not freeze.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"100μg","offer_id":43157315059891,"sku":"E-AB-F1011UE-100","price":266.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_1d0b9a35-6a12-4b7f-bb5a-306aebda1fba.png?v=1710513394","url":"https:\/\/afsbio.com\/products\/apc-anti-mouse-cd62l-antibody-mel14-e-ab-f1011ue","provider":"AFSBio Inc.","version":"1.0","type":"link"}