{"product_id":"apc-cyanine7-mouse-anti-human-cd3-monoclonal-antibody-a26219","title":"APC\/Cyanine7 Mouse anti-Human CD3 Monoclonal Antibody - A26219","description":"\u003cp\u003eAPC\/Cyanine7 Mouse anti-Human CD3 Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 100T, 2 x 100T, 5 x 100T\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: A26219-100, A26219-200, A26219-500\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha\/beta and gamma\/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women.\u003c\/p\u003e\n\n\u003cp\u003eCategory: Monoclonal Antibodies\u003c\/p\u003e\n\n\u003cp\u003eApplication: FC\u003c\/p\u003e\n\n\u003cp\u003eCross Reactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eProtein Weight: 23kDa Immunogen: Recombinant protein (or fragment).\u003c\/p\u003e\n\n\u003cp\u003eSpecies: Human\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 916\u003c\/p\u003e\n\n\u003cp\u003eSWISS: P07766\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: T3E; TCRE; IMD18; CD3epsilon\u003c\/p\u003e\n\n\u003cp\u003eSource: Mouse\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003ePurity: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eStorage: Store at 2-8℃. Avoid freeze.|Buffer: PBS with 0.09% Sodium azide,0.2% BSA,pH7.3.\u003c\/p\u003e\n\n\u003cp\u003eRecommended Dilution: FC,5 μl per 10^6 cells in 100 μl volume\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cell Biology Developmental Biology, Apoptosis, Immunology Inflammation, CDs, T Cell Receptor Signaling Pathway, Stem Cells, Hematopoietic Progenitors\u003c\/p\u003e\n\n\u003cp\u003eNCBI Alias: CD3E\u003c\/p\u003e\n\n\u003cp\u003eModifications: Unmodified\u003c\/p\u003e\n\n\u003cp\u003eConjugate: APC-Cy7. Ex:651nm. Em:779nm.\u003c\/p\u003e\n\n\u003cp\u003eClone Number Info: AMC50002\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ABclonal","offers":[{"title":"100T","offer_id":45189275451571,"sku":"A26219-100","price":347.2,"currency_code":"CAD","in_stock":true},{"title":"2 x 100T","offer_id":45189275484339,"sku":"A26219-200","price":599.2,"currency_code":"CAD","in_stock":true},{"title":"5 x 100T","offer_id":45189275517107,"sku":"A26219-500","price":1103.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_c2761abe-9e1b-42ec-b80b-f2f5091bd4e6.png?v=1766420683","url":"https:\/\/afsbio.com\/products\/apc-cyanine7-mouse-anti-human-cd3-monoclonal-antibody-a26219","provider":"AFSBio Inc.","version":"1.0","type":"link"}