{"product_id":"apc-polyclonal-antibody-bt-ap00506","title":"APC Polyclonal Antibody - BT-AP00506","description":"\u003cp\u003eAPC Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP00506-20, BT-AP00506-50, BT-AP00506-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: APC encodes a tumor suppressor protein that acts as an antagonist of the Wnt signaling pathway. It is also involved in other processes including cell migration and adhesion, transcriptional activation, and apoptosis. Defects in this gene cause familial adenomatous polyposis (FAP), an autosomal dominant pre-malignant disease that usually progresses to malignancy. Disease-associated mutations tend to be clustered in a small region designated the mutation cluster region (MCR) and result in a truncated protein product.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cell Biology\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: APC\u003c\/p\u003e\n\n\u003cp\u003eApplications: IHC-p, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: APC Antibody\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 311646\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: P25054; Mouse: Q61315\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: APC; DP2.5; Adenomatous polyposis coli protein; Protein APC; Deleted in polyposis 2.5\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 324\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45240112480435,"sku":"BT-AP00506-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45240112513203,"sku":"BT-AP00506-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45240112545971,"sku":"BT-AP00506-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_8a4451be-399b-4100-aef0-7c7f5e4005eb.png?v=1769403586","url":"https:\/\/afsbio.com\/products\/apc-polyclonal-antibody-bt-ap00506","provider":"AFSBio Inc.","version":"1.0","type":"link"}