{"product_id":"apc-rat-anti-mouse-cd49f-monoclonal-antibody-a28013","title":"APC Rat anti-Mouse CD49f Monoclonal Antibody - A28013","description":"\u003cp\u003eAPC Rat anti-Mouse CD49f Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 100T, 2 x 100T, 5 x 100T\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: A28013-100, A28013-200, A28013-500\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a protein that is a member of the integrin superfamily. Integrins are transmembrane receptors involved cell adhesion and signaling, and they are subdivided based on the heterodimer formation of alpha and beta chains. This protein has been shown to heterodimerize with beta 4 to bind laminin and to form the main component of hemidesmosomes, which mediate attachment of epithelia to basement membranes. In mouse, deficiency of this gene is associated with absence of hemidesmosomes, severe skin blistering, and early post-natal death. In humans mutations of this gene are associated with epidermolysis bullosa. Alternative splicing results in multiple transcript variants that encode different protein isoforms.\u003c\/p\u003e \n\n\u003cp\u003eCategory: Monoclonal Antibodies\u003c\/p\u003e\n\n\u003cp\u003eApplication: FC\u003c\/p\u003e\n\n\u003cp\u003eCross Reactivity: Mouse,Human\u003c\/p\u003e\n\n\u003cp\u003eProtein Weight: 122kDa Immunogen: Synthetic peptide.\u003c\/p\u003e \n\n\u003cp\u003eSpecies: Mouse\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 16403\u003c\/p\u003e\n\n\u003cp\u003eSWISS: Q61739\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: Cd49f; VLA-6; 5033401O05Rik\u003c\/p\u003e\n\n\u003cp\u003eSource: Rat\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003ePurity: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eStorage: Store at 2-8℃. Avoid freeze.|Buffer: PBS with 0.09% Sodium azide,0.2% BSA,pH7.3.\u003c\/p\u003e\n\n\u003cp\u003eRecommended Dilution: FC, ≤0.5 µg per million cells in 100 µl volume\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Signal Transduction Cytoskeleton \/ ECM Basal LaminaSignal Transduction Cytoskeleton \/ ECM Cell Adhesion Integrins AlphaStem Cells Embryonic Stem Cells Surface MoleculesStem Cells Hematopoietic Progenitors Myeloid Monocytic LineageDevelopmental Biology Embryogenesis Embryonic stem cells IntracellularNeuroscience Processes\u003c\/p\u003e\n\n\u003cp\u003eNCBI Alias: CD49f\u003c\/p\u003e\n\n\u003cp\u003eModifications: Unmodified\u003c\/p\u003e\n\n\u003cp\u003eConjugate: APC. Ex:650nm. Em:660nm.\u003c\/p\u003e\n\n\u003cp\u003eClone Number Info: ATC0036\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ABclonal","offers":[{"title":"100T","offer_id":45189335253171,"sku":"A28013-100","price":361.2,"currency_code":"CAD","in_stock":true},{"title":"2 x 100T","offer_id":45189335285939,"sku":"A28013-200","price":627.2,"currency_code":"CAD","in_stock":true},{"title":"5 x 100T","offer_id":45189335318707,"sku":"A28013-500","price":1397.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_c3cb4425-ad83-42ec-b5cf-8490429c4df3.png?v=1766421649","url":"https:\/\/afsbio.com\/products\/apc-rat-anti-mouse-cd49f-monoclonal-antibody-a28013","provider":"AFSBio Inc.","version":"1.0","type":"link"}