{"product_id":"apc-rat-anti-mouse-cd86-monoclonal-antibody-a27138","title":"APC Rat anti-Mouse CD86 Monoclonal Antibody - A27138","description":"\u003cp\u003eAPC Rat anti-Mouse CD86 Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 100T, 2 x 100T, 5 x 100T\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: A27138-100, A27138-200, A27138-500\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: Predicted to enable signaling receptor binding activity. Involved in several processes, including CD40 signaling pathway; activation of phospholipase C activity; and positive regulation of macromolecule metabolic process. Acts upstream of or within several processes, including cellular response to lipopolysaccharide; defense response to virus; and positive regulation of T cell proliferation. Located in external side of plasma membrane and intracellular membrane-bounded organelle. Is expressed in central nervous system and retina. Used to study Guillain-Barre syndrome. Human ortholog(s) of this gene implicated in several diseases, including Henoch-Schoenlein purpura; autoimmune disease (multiple); chronic lymphocytic leukemia; chronic obstructive pulmonary disease; and systemic scleroderma. Orthologous to human CD86 (CD86 molecule).\u003c\/p\u003e\n\n\u003cp\u003eCategory: Monoclonal Antibodies\u003c\/p\u003e\n\n\u003cp\u003eApplication: FC\u003c\/p\u003e\n\n\u003cp\u003eCross Reactivity: Mouse\u003c\/p\u003e\n\n\u003cp\u003eProtein Weight: 35kDa Immunogen: Recombinant protein (or fragment).\u003c\/p\u003e\n\n\u003cp\u003eSpecies: Mouse\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 12524\u003c\/p\u003e\n\n\u003cp\u003eSWISS: P42082\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: B7; B70; MB7; B7-2; B7.2; CLS1; Ly58; ETC-1; Ly-58; MB7-2; Cd28l2; TS\/A-2; CD86\u003c\/p\u003e\n\n\u003cp\u003eSource: Rat\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003ePurity: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eStorage: Store at 2-8℃. Avoid freeze.|Buffer: PBS with 0.09% Sodium azide,0.2% BSA,pH7.3.\u003c\/p\u003e\n\n\u003cp\u003eRecommended Dilution: FC,5 μl per 10^6 cells in 100 μl volume\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Immunology Adaptive Immunity T Cells CDImmunology Cell Type Markers CD Non-lineageMicrobiology Interspecies Interaction Host Virus InteractionStem Cells Hematopoietic Progenitors Lymphoid B Lymphocytic LineageStem Cells Hematopoietic Progenitors Myeloid Dendritic Cell LineageStem Cells Hematopoietic Progenitors Myeloid Monocytic LineageImmunology Adaptive Immunity Regulatory T Cells\u003c\/p\u003e\n\n\u003cp\u003eNCBI Alias: Cd86\u003c\/p\u003e\n\n\u003cp\u003eModifications: Unmodified\u003c\/p\u003e\n\n\u003cp\u003eConjugate: APC. Ex:650nm. Em:660nm.\u003c\/p\u003e\n\n\u003cp\u003eClone Number Info: ATC0032\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ABclonal","offers":[{"title":"100T","offer_id":45189332304051,"sku":"A27138-100","price":109.2,"currency_code":"CAD","in_stock":true},{"title":"2 x 100T","offer_id":45189332336819,"sku":"A27138-200","price":193.2,"currency_code":"CAD","in_stock":true},{"title":"5 x 100T","offer_id":45189332369587,"sku":"A27138-500","price":347.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_f4273d70-3243-4082-bf26-6e117669c629.png?v=1766421629","url":"https:\/\/afsbio.com\/products\/apc-rat-anti-mouse-cd86-monoclonal-antibody-a27138","provider":"AFSBio Inc.","version":"1.0","type":"link"}