{"product_id":"ape1-polyclonal-antibody-bz16836","title":"APE1 Polyclonal Antibody-BZ16836","description":"\u003cp\u003eAPE1 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eProduct: Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BZ16836-50, BZ16836-100\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: P27695\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC-P\u003c\/p\u003e\n\n\u003cp\u003eAll Applications: WB: 1\/500-1\/1000 IHC: 1\/50-1\/100\u003c\/p\u003e \n\n\u003cp\u003eBackground: Ape1 initiates the repair of abasic sites and is essential for the base excision repair (BER) pathway. Repair activities of Ape1 are stimulated by interaction with XRCC1, another essential protein in BER. Ape1 functions as a redox factor that maintains transcription factors in an active, reduced state but can also function in a redox-independent manner as a transcriptional cofactor to control different cellular fates such as apoptosis, proliferation and differentiation.\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: Affinity Purified\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: IgG\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 36 kDa; Observed MW: 36 kDa\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Western blot analysis of APE1 in K562 lysates using APE1 antibody.\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: APEX1; APE; APE1; APEX; APX; HAP1; REF1; DNA- (apurinic or apyrimidinic site) lyase; APEX nuclease; APEN; Apurinic-apyrimidinic endonuclease 1; AP endonuclease 1; APE-1; REF-1; Redox factor-1\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: A synthesized peptide derived from human APE1\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42916148805811,"sku":"BZ16836-50","price":342.59,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42916148838579,"sku":"BZ16836-100","price":589.65,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_151abb08-5363-45f4-a12f-350fedbc8224.jpg?v=1703417900","url":"https:\/\/afsbio.com\/products\/ape1-polyclonal-antibody-bz16836","provider":"AFSBio Inc.","version":"1.0","type":"link"}