{"product_id":"aplp-1-rabbit-pab-es3788","title":"APLP-1 rabbit pAb - ES3788","description":"\u003cp\u003eAPLP-1 rabbit pAb\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: ES3788-50, ES3788-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a member of the highly conserved amyloid precursor protein gene family. The encoded protein is a membrane-associated glycoprotein that is cleaved by secretases in a manner similar to amyloid beta A4 precursor protein cleavage. This cleavage liberates an intracellular cytoplasmic fragment that may act as a transcriptional activator. The encoded protein may also play a role in synaptic maturation during cortical development. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008],\u003c\/p\u003e \n\n\u003cp\u003eAlternate Name: APLP1; Amyloid-like protein 1; APLP; APLP-1\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB; IHC; IF; ELISA\u003c\/p\u003e\n\n\u003cp\u003eDilution: Western Blot: 1\/500 - 1\/2000. IHC-p: 1:100-300 ELISA: 1\/10000. Not yet tested in other applications.\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human; Mouse\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthesized peptide derived from APLP-1 . at AA range: 360-440\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eObserved Band (KD): 72kD\u003c\/p\u003e\n\n\u003cp\u003eHuman Gene ID: 333\u003c\/p\u003e\n\n\u003cp\u003eHuman SWISS Prot NO: P51693\u003c\/p\u003e\n\n\u003cp\u003eSubcellular Location: Cell membrane; Single-pass type I membrane protein.; [C30]: Cytoplasm. C-terminally processed in the Golgi complex.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ELK Bio","offers":[{"title":"50μL","offer_id":45202155372723,"sku":"ES3788-50","price":207.2,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45202155405491,"sku":"ES3788-100","price":347.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_360x_fb3fbcda-2283-4ff9-8a9c-eeb691e6b7bf.png?v=1767123185","url":"https:\/\/afsbio.com\/products\/aplp-1-rabbit-pab-es3788","provider":"AFSBio Inc.","version":"1.0","type":"link"}