{"product_id":"apoa-v-rabbit-pab-es4662","title":"ApoA-V rabbit pAb - ES4662","description":"\u003cp\u003eApoA-V rabbit pAb\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: ES4662-50, ES4662-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: The protein encoded by this gene is an apolipoprotein that plays an important role in regulating the plasma triglyceride levels, a major risk factor for coronary artery disease. It is a component of high density lipoprotein and is highly similar to a rat protein that is upregulated in response to liver injury. Mutations in this gene have been associated with hypertriglyceridemia and hyperlipoproteinemia type 5. This gene is located proximal to the apolipoprotein gene cluster on chromosome 11q23. Alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq, Oct 2009],\u003c\/p\u003e \n\n\u003cp\u003eAlternate Name: APOA5; RAP3; Apolipoprotein A-V; Apo-AV; ApoA-V; Apolipoprotein A5; Regeneration-associated protein 3\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB; ELISA\u003c\/p\u003e\n\n\u003cp\u003eDilution: Western Blot: 1\/500 - 1\/2000. ELISA: 1\/5000. Not yet tested in other applications.\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human; Rat; Mouse;\u003c\/p\u003e \n\n\u003cp\u003eImmunogen: Synthesized peptide derived from ApoA-V . at AA range: 30-110\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eObserved Band (KD): 41kD\u003c\/p\u003e\n\n\u003cp\u003eHuman Gene ID: 116519\u003c\/p\u003e\n\n\u003cp\u003eHuman SWISS Prot NO: Q6Q788\u003c\/p\u003e\n\n\u003cp\u003eSubcellular Location: Secreted. Early endosome. Late endosome. Golgi apparatus trans-Golgi network. In the presence of SORL1, internalized to early endosomes, sorted in a retrograde fashion to late endosomes, from which a portion is sent to lysosomes and degradation, another portion is sorted to the trans-Golgi network.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ELK Bio","offers":[{"title":"50μL","offer_id":45202208227507,"sku":"ES4662-50","price":207.2,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45202208260275,"sku":"ES4662-100","price":347.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_360x_87f8b457-d90e-4410-afba-ba389e303b5b.png?v=1767124269","url":"https:\/\/afsbio.com\/products\/apoa-v-rabbit-pab-es4662","provider":"AFSBio Inc.","version":"1.0","type":"link"}