{"product_id":"apoa1-monoclonal-antibody-bt-mca4399","title":"APOA1 Monoclonal Antibody - BT-MCA4399","description":"\u003cp\u003eAPOA1 Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Number: BT-MCA4399-50, BT-MCA4399-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: APOA1: apolipoprotein A-I, it is the major protein component of high density lipoprotein (HDL) in plasma. The protein promotes cholesterol efflux from tissues to the liver for excretion, and it is a cofactor for lecithin cholesterolacyltransferase (LCAT) which is responsible for the formation of most plasma cholesteryl esters. Defects in the Apolipoprotein A I gene are associated with HDL deficiency and Tangier disease. The therapeutic potential of apoA-I has been recently assessed in patients with acute coronary syndromes, using a recombinant form of a naturally occurring variant of apoA-I. The availability of recombinant normal apoA-I should facilitate further investigation into the potential usefulness of apoA-I in preventing atherosclerotic vascular diseases.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cardiovascular, Neuroscience\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: APOA1\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eClonality: Monoclonal\u003c\/p\u003e\n\n\u003cp\u003eClone ID: 5F4F5\u003c\/p\u003e \n\n\u003cp\u003eHost: Mouse\u003c\/p\u003e\n\n\u003cp\u003eIsotype: Mouse IgG1\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: APOA1\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Purified recombinant fragment of human APOA1 expressed in E. Coli.\u003c\/p\u003e\n\n\u003cp\u003eStorage: 4°C|-20°C for long term storage\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Ascitic fluid containing 0.03% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 25kDa\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: P02647\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: MGC117399\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"50μL","offer_id":45238354608307,"sku":"BT-MCA4399-50","price":308.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45238354641075,"sku":"BT-MCA4399-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_f418f8d2-51bf-4715-890a-55e566600e43.png?v=1769379023","url":"https:\/\/afsbio.com\/products\/apoa1-monoclonal-antibody-bt-mca4399","provider":"AFSBio Inc.","version":"1.0","type":"link"}