{"product_id":"apob-rabbit-polyclonal-antibody-ra21981","title":"APOB Rabbit Polyclonal Antibody - RA21981","description":"APOB Rabbit Polyclonal Antibody\n\nSizes: 50μL, 100μL\n\nCatalogue Numbers: RA21981-50, RA21981-100\n\nCitations, Manuals and MSDS Available upon request.\n\nBackground: apolipoprotein B (APOB) Homo sapiens This gene product is the main apolipoprotein of chylomicrons and low density lipoproteins. It occurs in plasma as two main isoforms, apoB-48 and apoB-100: the former is synthesized exclusively in the gut and the latter in the liver. The intestinal and the hepatic forms of apoB are encoded by a single gene from a single, very long mRNA. The two isoforms share a common N-terminal sequence. The shorter apoB-48 protein is produced after RNA editing of the apoB-100 transcript at residue 2180 (CAA-\u0026gt;UAA), resulting in the creation of a stop codon, and early translation termination. Mutations in this gene or its regulatory region cause hypobetalipoproteinemia, normotriglyceridemic hypobetalipoproteinemia, and hypercholesterolemia due to ligand-defective apoB, diseases affecting plasma cholesterol and apoB levels. [provided by RefSeq, Jul 2008],\n\nCondition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\n\nStorage Instructions: -20°C\/1 year\n\nRecommended dilutions: WB 1:1000-2000 ELISA 1:5000-20000\n\nAlternative Names: Apolipoprotein B-100 (Apo B-100) [Cleaved into: Apolipoprotein B-48 (Apo B-48) ]\n\nApplications: WB; ELISA\n\nSpecies Cross-Reactivity: Human; Rat; Mouse\n\nGeneID (Human): 338\n\nSWISS: P04114\n\nSource: Rabbit\n\nResearch Use Only","brand":"Reed Bio","offers":[{"title":"50μL","offer_id":45119702892723,"sku":"RA21981-50","price":336.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45119702925491,"sku":"RA21981-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_e89ad8d1-0a67-4a79-8918-b93160f749d3.png?v=1773356214","url":"https:\/\/afsbio.com\/products\/apob-rabbit-polyclonal-antibody-ra21981","provider":"AFSBio Inc.","version":"1.0","type":"link"}