{"product_id":"apoe-polyclonal-antibody-bt-ap00533","title":"ApoE Polyclonal Antibody - BT-AP00533","description":"\u003cp\u003eApoE Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP00533-20, BT-AP00533-50, BT-AP00533-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: The protein encoded by APOE is a major apoprotein of the chylomicron. It binds to a specific liver and peripheral cell receptor, and is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. This gene maps to chromosome 19 in a cluster with the related apolipoprotein C1 and C2 genes. Mutations in this gene result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III), in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Neuroscience; Cardiovascular\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: APOE\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: ApoE Antibody\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 36154\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: P02649; Mouse: P08226\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: APOE; Apolipoprotein E; Apo-E\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 348\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45240114446515,"sku":"BT-AP00533-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45240114479283,"sku":"BT-AP00533-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45240114512051,"sku":"BT-AP00533-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_4ea42843-0163-49a3-8726-accde21dceb9.png?v=1769403624","url":"https:\/\/afsbio.com\/products\/apoe-polyclonal-antibody-bt-ap00533","provider":"AFSBio Inc.","version":"1.0","type":"link"}