{"product_id":"apoe-rabbit-pab-a27419","title":"Apoe Rabbit pAb - A27419","description":"\u003cp\u003eApoe Rabbit pAb\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: A27419-20, A27419-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a member of the apolipoprotein A1\/A4\/E family of proteins. This protein is involved in the transport of lipoproteins in the blood. It binds to a specific liver and peripheral cell receptor, and is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. Homozygous knockout mice for this gene accumulate high levels of cholesterol in the blood and develop atherosclerosis. Different alleles of this gene have been associated with either increased risk or a protective effect for Alzheimer's disease in human patients. This gene maps to chromosome 7 in a cluster with the related apolipoprotein C1, C2 and C4 genes.\u003c\/p\u003e\n\n\u003cp\u003eCategory: Polyclonal Antibodies\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IF-P, IHC-P, ELISA\u003c\/p\u003e\n\n\u003cp\u003eCross-reactivity: Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eProtein Weight: 36kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved Molecular Weight: 35kDa\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant protein (or fragment) .\u003c\/p\u003e\n\n\u003cp\u003eSpecies: Mouse\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 11816\u003c\/p\u003e\n\n\u003cp\u003eSWISS: P08226\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: Apo-E\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003ePurity: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eStorage: Store at -20℃. Avoid freeze \/ thaw cycles. Buffer: PBS with 0.09% Sodium azide, 50% glycerol, pH 7.3.\u003c\/p\u003e\n\n\u003cp\u003eRecommended Dilutions: WB, 1:1000 - 1:4000 IF-P, 1:100 - 1:400 IHC-P, 1:200 - 1:800 ELISA, Recommended starting concentration is 1 μg\/mL. Please optimize the concentration based on your specific assay requirements.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cholesterol metabolism, host-virus interaction, lipid metabolism, lipid transport, steroid metabolism, sterol metabolism, transport, heparin binding\u003c\/p\u003e\n\n\u003cp\u003eNCBI Alias: Apoe\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ABclonal","offers":[{"title":"20uL","offer_id":45189886345395,"sku":"A27419-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"100uL","offer_id":45189886378163,"sku":"A27419-100","price":417.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_c2f7181c-c4ff-4964-90fe-8ac8c415e64d.png?v=1766437470","url":"https:\/\/afsbio.com\/products\/apoe-rabbit-pab-a27419","provider":"AFSBio Inc.","version":"1.0","type":"link"}