{"product_id":"app-bp2-rabbit-pab-es8357","title":"APP-BP2 rabbit pAb - ES8357","description":"\u003cp\u003eAPP-BP2 rabbit pAb\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: ES8357-50, ES8357-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: The protein encoded by this gene interacts with microtubules and is functionally associated with beta-amyloid precursor protein transport and\/or processing. The beta-amyloid precursor protein is a cell surface protein with signal-transducing properties, and it is thought to play a role in the pathogenesis of Alzheimer's disease. The encoded protein may be involved in regulating cell death. This gene has been found to be highly expressed in breast cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013],\u003c\/p\u003e \n\n\u003cp\u003eAlternate Name: APPBP2; KIAA0228; PAT1; Amyloid protein-binding protein 2; Amyloid beta precursor protein-binding protein 2; APP-BP2; Protein interacting with APP tail 1\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB; ELISA\u003c\/p\u003e\n\n\u003cp\u003eDilution: Western Blot: 1\/500 - 1\/2000. ELISA: 1\/10000. Not yet tested in other applications.\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human; Mouse; Rat\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthesized peptide derived from APP-BP2 . at AA range: 390-470\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eObserved Band (KD): 67kD\u003c\/p\u003e\n\n\u003cp\u003eHuman Gene ID: 10513\u003c\/p\u003e\n\n\u003cp\u003eHuman SWISS Prot NO: Q92624\u003c\/p\u003e\n\n\u003cp\u003eSubcellular Location: Nucleus. Cytoplasm, cytoskeleton. Membrane; Peripheral membrane protein. Associated with membranes and microtubules.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ELK Bio","offers":[{"title":"50μL","offer_id":45202375082163,"sku":"ES8357-50","price":207.2,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45202375114931,"sku":"ES8357-100","price":347.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_360x_6b430314-7536-4416-8797-9ca0f886aae0.png?v=1767127795","url":"https:\/\/afsbio.com\/products\/app-bp2-rabbit-pab-es8357","provider":"AFSBio Inc.","version":"1.0","type":"link"}