{"product_id":"appl1-polyclonal-antibody-e-ab-63089","title":"APPL1 Polyclonal Antibody - E-AB-63089","description":"\u003cp\u003eAPPL1 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-63089-60, E-AB-63089-120, E-AB-63089-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: APPL1\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: APPL1; APPL; DIP13alpha; MODY14\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cancer, Cell Biology, Developmental Biology, Neuroscience, Signal Transduction\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplication: WB\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n \n\n\u003cp\u003eUNIProt ID: Q9UKG1\u003c\/p\u003e\n\n\u003cp\u003eBackground: The protein encoded by this gene has been shown to be involved in the regulation of cell proliferation, and in the crosstalk between the adiponectin signalling and insulin signalling pathways. The encoded protein binds many other proteins, including RAB5A, DCC, AKT2, PIK3CA, adiponectin receptors, and proteins of the NuRD\/MeCP1 complex. This protein is found associated with endosomal membranes, but can be released by EGF and translocated to the nucleus.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant fusion protein of human APPL1 (NP_036228.1).\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB \t1:500-1:2000\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 79kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 95kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"60μL","offer_id":43146275225779,"sku":"E-AB-63089-60","price":280.0,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43146275258547,"sku":"E-AB-63089-120","price":448.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43146275291315,"sku":"E-AB-63089-200","price":742.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_879613a8-e645-438a-bd74-8b82f043ec9a.png?v=1710292827","url":"https:\/\/afsbio.com\/products\/appl1-polyclonal-antibody-e-ab-63089","provider":"AFSBio Inc.","version":"1.0","type":"link"}