{"product_id":"aqp2-rabbit-pab-es1688","title":"AQP2 rabbit pAb - ES1688","description":"\u003cp\u003eAQP2 rabbit pAb\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: ES1688-50, ES1688-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a water channel protein located in the kidney collecting tubule. It belongs to the MIP\/aquaporin family, some members of which are clustered together on chromosome 12q13. Mutations in this gene have been linked to autosomal dominant and recessive forms of nephrogenic diabetes insipidus. [provided by RefSeq, Oct 2008],\u003c\/p\u003e \n\n\u003cp\u003eAlternate Name: AQP2; Aquaporin-2; AQP-2; ADH water channel; Aquaporin-CD; AQP-CD; Collecting duct water channel protein; WCH-CD; Water channel protein for renal collecting duct\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB; IHC; IF; ELISA\u003c\/p\u003e\n\n\u003cp\u003eDilution: Western Blot: 1\/500 - 1\/2000. Immunohistochemistry: 1\/100 - 1\/300. Immunofluorescence: 1\/200 - 1\/1000. ELISA: 1\/10000. Not yet tested in other applications.\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human; Mouse; Rat; Monkey; Dog\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human Aquaporin 2. AA range:222-271\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eObserved Band (KD): 29kD\u003c\/p\u003e\n\n\u003cp\u003eHuman Gene ID: 359\u003c\/p\u003e\n\n\u003cp\u003eHuman SWISS Prot NO: P41181\u003c\/p\u003e\n\n\u003cp\u003eSubcellular Location: Apical cell membrane; Multi-pass membrane protein. Basolateral cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. Cytoplasmic vesicle membrane; Multi-pass membrane protein. Golgi apparatus trans-Golgi network membrane; Multi-pass membrane protein. Shuttles from vesicles to the apical membrane (PubMed:15509592). Vasopressin-regulated phosphorylation is required for translocation to the apical cell membrane (PubMed:15509592). PLEKHA8\/FAPP2 is required to transport AQP2 from the TGN to sites where AQP2 is phosphorylated (By similarity).\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ELK Bio","offers":[{"title":"50μL","offer_id":45202030526643,"sku":"ES1688-50","price":207.2,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45202030559411,"sku":"ES1688-100","price":347.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_360x_21502a05-5d0b-4b69-909c-52e53c9e8e90.png?v=1767120267","url":"https:\/\/afsbio.com\/products\/aqp2-rabbit-pab-es1688","provider":"AFSBio Inc.","version":"1.0","type":"link"}