{"product_id":"ar-beta2-polyclonal-antibody-bt-ap00655","title":"AR-Beta2 Polyclonal Antibody - BT-AP00655","description":"\u003cp\u003eAR-Beta2 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP00655-20, BT-AP00655-50, BT-AP00655-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: ADRB2 encodes beta-2-adrenergic receptor which is a member of the G protein-coupled receptor superfamily. This receptor is directly associated with one of its ultimate effectors, the class C L-type calcium channel Ca (V)1.2. This receptor-channel complex also contains a G protein, an adenylyl cyclase, cAMP-dependent kinase, and the counterbalancing phosphatase, PP2A. The assembly of the signaling complex provides a mechanism that ensures specific and rapid signaling by this G protein-coupled receptor. ADRB2 is intronless. Different polymorphic forms, point mutations, and\/or downregulation of this gene are associated with nocturnal asthma, obesity and type 2 diabetes.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Signal Transduction\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: ADRB2\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC-p, IF, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: AR-beta2 Antibody\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 46557\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: P07550; Mouse: P18762; Rat: P10608\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: ADRB2; ADRB2R; B2AR; Beta-2 adrenergic receptor; Beta-2 adrenoreceptor; Beta-2 adrenoceptor\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 154; Mouse: 11555\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45240123687091,"sku":"BT-AP00655-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45240123719859,"sku":"BT-AP00655-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45240123752627,"sku":"BT-AP00655-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_c9ee0675-02bc-4867-905e-64b0a619c419.png?v=1769403777","url":"https:\/\/afsbio.com\/products\/ar-beta2-polyclonal-antibody-bt-ap00655","provider":"AFSBio Inc.","version":"1.0","type":"link"}